Antimuscarinic effects of antihistamines: quantitative evaluation by receptor-binding assay

K Nobuo, O SHIRAKAWA, K Takayoshi… - Japanese journal of …, 1987 - Elsevier
Quantitative evaluation of antimuscarinic effects of antihistamines (H 1 and H 2 -receptor
antagonists) was carried out using a receptor-binding assay. The inhibition constants (K 1 …

Selective thermocoagulation of unresectable pancreatic cancers by using radiofrequency capacitive heating

…, A Nakagawa, Y Kamiyama, K Yamamoto, N Kubo… - Pancreas, 2000 - journals.lww.com
Recent investigations indicated that hyperthermia has antitumor effects. Several interstitial
hyperthermic techniques were developed, and their clinical usefulness and safety were …

Subjective results of laser surgery for allergic rhinitis

S Kawamura, T Fukutake, N Kubo… - Acta Oto …, 1993 - Taylor & Francis
Inferior turbinates of 389 patients with perennial allergic rhinitis were vaporized by a defocused
carbon dioxide (CO 2 ) laser beam, using specially designed handpieces. This laser …

Transient receptor potential channels in the inner ear: presence of transient receptor potential channel subfamily 1 and 4 in the guinea pig inner ear

M Takumida, N Kubo, M Ohtani, Y Suzuka… - Acta oto …, 2005 - Taylor & Francis
Conclusion. The results of this study indicate that transient receptor potential subfamily 1 (TRPV1)
may play a functional role in sensory cell physiology and that TRPV4 may be …

Characteristics of polycrystalline-Si thin film transistors fabricated by excimer laser annealing method

N Kubo, N Kusumoto, T Inushima… - IEEE Transactions on …, 1994 - ieeexplore.ieee.org
The electrical characteristics of excimer laser annealed (ELA) polycrystalline-Si thin film
transistors (poly-Si TFT's) were investigated. These results were compared to those of poly-Si …

Functional expression of transient receptor potential vanilloid 4 in the mouse cochlea

J Shen, N Harada, N Kubo, B Liu, A Mizuno… - …, 2006 - journals.lww.com
Transient receptor potential vanilloid 4, the Ca 2+-permeable cation channel has been
proposed as an osmosensitive and a mechanosensitive channel. We investigated functional …

Brain histamine H1 receptor occupancy of loratadine measured by positron emission topography: comparison of H1 receptor occupancy and proportional impairment …

N Kubo, M Senda, Y Ohsumi… - Human …, 2011 - Wiley Online Library
Aims We have evaluated the sedative properties of H1‐antihistamines by using positron
emission tomography (PET) and 11 C‐doxepin. The purpose of the present study was to …

Hyposmotic stimulation-induced nitric oxide production in outer hair cells of the guinea pig cochlea

H Takeda-Nakazawa, N Harada, J Shen, N Kubo… - Hearing research, 2007 - Elsevier
Nitric oxide (NO) production during hyposmotic stimulation in outer hair cells (OHCs) of the
guinea pig cochlea was investigated using the NO sensitive dye DAF-2. Simultaneous …

Effects of topical capsaicin on autonomic nerves in experimentally-induced nasal hypersensitivity: an immunocytochemical study

M Kitajiri, N Kubo, H Ikeda, K Sato… - Acta Oto …, 1993 - Taylor & Francis
Effects of capsaicin on autonomic nerves in the nasal mucosa and olfactory bulb of toluene
diisocyanate sensitized guinea pigs were studied using immunocytochemistry. In the nasal …

Effects of various inflammatory mediators on eustachian tube patency

T Minami, N Kubo, K Tomoda… - Acta oto …, 1992 - Taylor & Francis
The effects of several inflammatory mediators on the patency of the Eustachian tube were
evaluated in 15 mongrel dogs. Histamine, leukotriene C 4 (LTC 4 ) and D 4 (LTD 4 ), and …