Why most acute stroke studies are positive in animals but not in patients: a systematic comparison of preclinical, early phase, and phase 3 clinical trials of …

…, JK Strecker, J Wellmann, NM Bruckmann… - Annals of …, 2020 - Wiley Online Library
Objective To analyze why numerous acute stroke treatments were successful in the
laboratory but failed in large clinical trials. Methods We searched all phase 3 trials of medical …

[HTML][HTML] Comparison of nodal staging between CT, MRI, and [18F]-FDG PET/MRI in patients with newly diagnosed breast cancer

J Morawitz, NM Bruckmann, F Dietzel, T Ullrich… - European journal of …, 2022 - Springer
Purpose To compare CT, MRI, and [ 18 F]-fluorodeoxyglucose positron emission tomography
([ 18 F]-FDG PET/MRI) for nodal status, regarding quantity and location of metastatic …

[HTML][HTML] Prospective comparison of the diagnostic accuracy of 18F-FDG PET/MRI, MRI, CT, and bone scintigraphy for the detection of bone metastases in the initial …

NM Bruckmann, J Kirchner, L Umutlu, WP Fendler… - European …, 2021 - Springer
Objectives To compare the diagnostic performance of [ 18 F]FDG PET/MRI, MRI, CT, and
bone scintigraphy for the detection of bone metastases in the initial staging of primary breast …

[HTML][HTML] Multiparametric Integrated 18F-FDG PET/MRI-Based Radiomics for Breast Cancer Phenotyping and Tumor Decoding

L Umutlu, J Kirchner, NM Bruckmann, J Morawitz… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is considered the leading cancer type and main cause of
cancer death in women. In this study, we assess simultaneous 18 F-FDG PET/MRI of the breast …

[HTML][HTML] Multiparametric 18F-FDG PET/MRI-Based Radiomics for Prediction of Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Cancer

L Umutlu, J Kirchner, NM Bruckmann, J Morawitz… - Cancers, 2022 - mdpi.com
Simple Summary In breast cancer, the leading cancer type and the main cause of cancer
death in women, achieving pathological complete response after neoadjuvant chemotherapy …

[HTML][HTML] Prospective evaluation of whole-body MRI and 18F-FDG PET/MRI in N and M staging of primary breast cancer patients

NM Bruckmann, LM Sawicki, J Kirchner… - European Journal of …, 2020 - Springer
Objectives To evaluate and compare the diagnostic potential of whole-body MRI and whole-body
18 F-FDG PET/MRI for N and M staging in newly diagnosed, histopathologically …

Targeting different monocyte/macrophage subsets has no impact on outcome in experimental stroke

A Schmidt, JK Strecker, S Hucke, NM Bruckmann… - Stroke, 2017 - Am Heart Assoc
Background and Purpose— Peripheral immune cell infiltration contributes to neural injury
after ischemic stroke. However, in contrast to lymphocytes and neutrophils, the role of different …

[HTML][HTML] Prospective comparison of CT and 18F-FDG PET/MRI in N and M staging of primary breast cancer patients: Initial results

NM Bruckmann, J Kirchner, J Morawitz, L Umutlu… - PLoS …, 2021 - journals.plos.org
Objectives To compare the diagnostic accuracy of contrast-enhanced thoraco-abdominal
computed tomography and whole-body 18 F-FDG PET/MRI in N and M staging in newly …

[HTML][HTML] Towards a fast PET/MRI protocol for breast cancer imaging: maintaining diagnostic confidence while reducing PET and MRI acquisition times

K Jannusch, ME Lindemann, NM Bruckmann… - European …, 2023 - Springer
Objectives To investigate the diagnostic feasibility of a shortened breast PET/MRI protocol
in breast cancer patients. Methods Altogether 90 women with newly diagnosed T1 tumor-…

A role of PET/MR in breast cancer?

NM Bruckmann, J Morawitz, WP Fendler… - Seminars in Nuclear …, 2022 - Elsevier
PET/MRI has been available since 2010, representing the newest of the hybrid imaging
modalities. It combines functional as well as morphologic high-resolution MRI data with …