18F-DCFBC PET/CT for PSMA-based detection and characterization of primary prostate cancer

…, TC Cornish, N Gonzalez-Roibon… - Journal of Nuclear …, 2015 - Soc Nuclear Med
We previously demonstrated the ability to detect metastatic prostate cancer using N-[N-[(S)-1,3-dicarboxypropyl]carbamoyl]-4-
18 F-fluorobenzyl-l-cysteine ( 18 F-DCFBC), a low-…

[HTML][HTML] Loss of PTEN expression is associated with increased risk of recurrence after prostatectomy for clinically localized prostate cancer

A Chaux, SB Peskoe, N Gonzalez-Roibon, L Schultz… - Modern pathology, 2012 - Elsevier
PTEN (phosphatase and tensin homolog on chromosome 10) is one of the most frequently
lost tumor suppressor genes in human cancers and it has been described in more than two-…

Determination of the nonlethal margin inside the visible “ice-ball” during percutaneous cryoablation of renal tissue

…, C Weiss, A Chaux, N Gonzalez-Roibon… - Cardiovascular and …, 2013 - Springer
Objective The study was designed to determine the distance between the visible “ice-ball”
and the lethal temperature isotherm for normal renal tissue during cryoablation. Methods The …

GATA binding protein 3 is down-regulated in bladder cancer yet strong expression is an independent predictor of poor prognosis in invasive tumor

…, Y Li, Q Yang, LA McMahon, N Gonzalez-Roibon… - Human pathology, 2012 - Elsevier
Although GATA binding protein 3, a zinc finger transcription factor and an estrogen receptor–regulated
gene, has recently been suggested as a marker for urothelium, prognostic …

Utility of uroplakin II expression as a marker of urothelial carcinoma

…, H Miyamoto, A Cimino-Mathews, N Gonzalez-Roibon… - Human pathology, 2015 - Elsevier
Uroplakins are markers of terminally differentiated urothelium. Uroplakin II (UPII) is a newly
described sensitive marker for urothelial carcinoma (UC). The expression profile of UPII in …

Human papillomavirus infection and immunohistochemical p16INK4a expression as predictors of outcome in penile squamous cell carcinomas

…, MW Ball, SF Faraj, E Munari, N Gonzalez-Roibon… - Human pathology, 2015 - Elsevier
Approximately 50% of penile squamous cell carcinomas (SCC) are associated with high-risk
human papillomavirus (HR-HPV) infection. We evaluated the correlation of p16 INK4a …

Immunohistochemical expression of SALL4 in hepatocellular carcinoma, a potential pitfall in the differential diagnosis of yolk sac tumors

N Gonzalez-Roibon, B Katz, A Chaux, R Sharma… - Human pathology, 2013 - Elsevier
SALL4 is a transcription factor that serves as a marker of yolk sac tumor. Yolk sac tumor and
hepatocellular carcinoma share histologic, serologic, and immunohistochemical features. …

Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma

…, S Begum, C Michailidi, N Gonzalez-Roibon… - Cell Cycle, 2013 - Taylor & Francis
Urothelial cell carcinoma (UCC) is the second most common genitourinary malignant disease
in the USA, and tobacco smoking is the major known risk factor for UCC development. …

The role of GATA binding protein 3 in the differential diagnosis of collecting duct and upper tract urothelial carcinomas

N Gonzalez-Roibon, R Albadine, R Sharma, SF Faraj… - Human pathology, 2013 - Elsevier
Differential diagnosis of collecting duct carcinoma (CDC) from invasive upper tract urothelial
carcinoma (UTUC) can be challenging. PAX8 and p63 are 2 markers often used in this …

[HTML][HTML] Global 5-hydroxymethylcytosine levels are profoundly reduced in multiple genitourinary malignancies

…, D Taheri, S Karram, SM Bezerra, N Gonzalez Roibon… - PloS one, 2016 - journals.plos.org
Solid tumors are characterized by a plethora of epigenetic changes. In particular, patterns
methylation of cytosines at the 5-position (5mC) in the context of CpGs are frequently altered in …