Purpose: We recently reported that anionic phospholipids, principally phosphatidylserine,
become exposed on the external surface of vascular endothelial cells in tumors, probably in …

Benzyloxy-2-chloroquinoline was reacted with fluorine-18 labelled potassium cryptand
fluoride, followed by catalytic hydrogenation to prepare [18F]2-fluoroquinolin-8-ol in high …

Bioluminescent imaging (BLI) of luciferase‐expressing cells in live small animals is a powerful
technique for investigating tumor growth, metastasis, and specific biological molecular …

Bioluminescent imaging (BLI) of cells expressing luciferase is a valuable noninvasive
technique for investigating molecular events and tumor dynamics in the living animal. Current …

The electron-multiplying charge-coupled device (EMCCD) offers improved quantum efficiencies
(40 to 95%) over a broader range of wavelengths (400 to 900 nm) and a higher intrinsic …

Modern positron emission tomography (PET) systems, offering high counting rate
capabilities, high sensitivity, and near-submillimeter coordinate resolution, require fast image …

Purpose To study the feasibility of using an iterative reconstruction algorithm to improve
previously reconstructed CT images which are judged to be non-diagnostic on clinical review. A …

Objective Bioluminescent imaging is a valuable noninvasive technique for investigating tumor
dynamics and specific biological molecular events in living animals to better understand …

Purpose To test and evaluate an efficient iterative image processing strategy to improve the
quality of sub-optimal pre-clinical PET images. A novel iterative resolution subsets-based …

A small-animal PET imaging device has been developed at the University of Texas
Southwestern Medical Center at Dallas using scintillating 1-mm round BCF10 fibers and small …