An interindividual comparison of O-(2-[18F] Fluoroethyl)-L-Tyrosine (FET)–and L-[Methyl-11C] methionine (MET)–PET in patients with brain gliomas and metastases

…, ST Astner, E Riedel, C Nieder, N Wiedenmann… - International Journal of …, 2011 - Elsevier
PURPOSE: L-[methyl- 11 C]methionine (MET)–positron emission tomography (PET) has a
high sensitivity and specificity for imaging of gliomas and metastatic brain tumors. The short …

Hypoxia imaging with FAZA-PET and theoretical considerations with regard to dose painting for individualization of radiotherapy in patients with head and neck cancer

…, B Röper, M Dobritz, N Wiedenmann… - International Journal of …, 2007 - Elsevier
PURPOSE: To evaluate the role of hypoxia positron emission tomography (PET) using [ 18 F]fluoroazomycin-arabinoside
(FAZA) in head and neck cancer for radiation treatment …

Long-term outcome after highly advanced single-dose or fractionated radiotherapy in patients with vestibular schwannomas–pooled results from 3 large German …

…, C Engelhard, C Kopp, N Wiedenmann… - Radiotherapy and …, 2015 - Elsevier
Purpose To evaluate long-term clinical outcome and determine prognostic factors for local-control,
hearing preservation and cranial nerve toxicity in 449 patients treated for 451 …

Validation of a method for automatic image fusion (BrainLAB System) of CT data and 11C-methionine-PET data for stereotactic radiotherapy using a LINAC: first …

AL Grosu, R Lachner, N Wiedenmann, S Stärk… - International Journal of …, 2003 - Elsevier
PURPOSE: (a) To implement a fully automatic method to integrate 11 C-methionine positron
emission tomography (MET-PET) data into stereotactic radiation treatment planning using …

Serial [18F]-fluoromisonidazole PET during radiochemotherapy for locally advanced head and neck cancer and its correlation with outcome

NE Wiedenmann, S Bucher, M Hentschel, M Mix… - Radiotherapy and …, 2015 - Elsevier
Purpose The aim was to assess changes of tumour hypoxia during primary radiochemotherapy
(RCT) for head and neck cancer (HNC) and to evaluate their relationship with treatment …

Whole brain irradiation with hippocampal sparing and dose escalation on multiple brain metastases: a planning study on treatment concepts

V Prokic, N Wiedenmann, F Fels, M Schmucker… - International Journal of …, 2013 - Elsevier
PURPOSE: To develop a new treatment planning strategy in patients with multiple brain
metastases. The goal was to perform whole brain irradiation (WBI) with hippocampal sparing …

Radiotherapy for high-grade gliomas

…, N Andratschke, N Wiedenmann… - Strahlentherapie …, 2004 - search.proquest.com
The publication of Radiation Therapy Oncology Group (RTOG) Study 83-02 in 1996 stimulated
further investigations of altered fractionation, ie, application of more than one fraction per …

Current status of angiogenesis inhibitors combined with radiation therapy

C Nieder, N Wiedenmann, N Andratschke… - Cancer treatment …, 2006 - Elsevier
Angiogenesis inhibitors combined with cytotoxic chemotherapy have recently entered routine
oncological practice. Several rationales exist for combining these agents with ionizing …

Exploratory geographical analysis of hypoxic subvolumes using 18F-MISO-PET imaging in patients with head and neck cancer in the course of primary …

MI Bittner, N Wiedenmann, S Bucher… - Radiotherapy and …, 2013 - Elsevier
Background and purpose Hypoxia in head and neck tumours is associated with poor prognosis
and outcome, and can be visualized using 18 F-MISO-PET imaging; however, it is not …

The utility of multiparametric MRI to characterize hypoxic tumor subvolumes in comparison to FMISO PET/CT. Consequences for diagnosis and chemoradiation …

N Wiedenmann, AL Grosu, M Büchert… - Radiotherapy and …, 2020 - Elsevier
Background and Purpose Hypoxia is an essential metabolic marker that determines chemo-
and radiation resistance in head-and-neck squamous cell carcinoma (HNSCC) patients. …