Metabolism is a fundamental process of life. However, non-invasive measurement of local
tissue metabolism is limited today by a deficiency in adequate tools for in vivo observations. …

Efficient delivery of short interfering RNAs reflects a prerequisite for the development of RNA
interference therapeutics. Here, we describe highly specific nanoparticles, based on near …

Multispectral optoacoustic tomography (MSOT) is a powerful modality that allows high-resolution
imaging of photo-absorbers deep within tissue, beyond the classical depth and …

A functional cancer theranostic nanoplatform is developed, specifically tailored toward the
optoacoustic modality by combining gold nanorods with DNA nanostructures (D-AuNR). DNA …

Early detection of cancer greatly increases the chances of a simpler and more effective treatment.
Traditional imaging techniques are often limited by shallow penetration, low sensitivity, …

Purpose To investigate whether multispectral optoacoustic tomography (MSOT) can reveal
the heterogeneous distributions of exogenous agents of interest and vascular characteristics …

Brain research depends strongly on imaging for assessing function and disease in vivo. We
examine herein multispectral opto-acoustic tomography (MSOT), a novel technology for high-…

Indocyanine green (ICG) is an FDA-approved, strongly photo-absorbent/fluorescent probe
that has been incorporated into a clinically-relevant PEGylated liposome as a flexible …

Difficulty in visualizing glioma margins intraoperatively remains a major issue in the achievement
of gross total tumor resection and, thus, better clinical outcome of glioblastoma (GBM) …

We have synthesized a targeted imaging agent for rheumatoid arthritis based on polysulfated
gold nanorods. The CTAB layer on gold nanorods was first replaced with PEG-thiol and …