Self-renewing tissue-resident macrophages are thought to be exclusively derived from
embryonic progenitors. However, whether circulating monocytes can also give rise to such …

Branched gold nanoparticles are potential photothermal therapy agents because of their large
absorption cross section in the near-infrared window. Upon laser irradiation they produce …

Human epidermal growth factor receptor 2 (HER2) status is one of the major tumor characteristics
in breast cancer to guide therapy. Anti-HER2 treatment has clear survival advantages …

Nanobodies are recombinant, antigen-specific, single-domain, variable fragments of camelid
heavy chain-only antibodies. The innate supremacy of nanobodies as a renewable source …

Accurate determination of tumor human epidermal growth factor receptor 2 (HER2)‐status in
breast cancer patients is possible via noninvasive imaging, provided adequate tracers are …

Tumor-associated macrophages (TAM) are an important component of the tumor stroma
and exert several tumor-promoting activities. Strongly pro-angiogenic TAMs that reside in …

Rationale: A noninvasive tool allowing the detection of vulnerable atherosclerotic plaques is
highly needed. By combining nanomolar affinities and fast blood clearance, nanobodies …

Nanobodies are the smallest fully functional antigen-binding antibody fragments possessing
ideal properties as probes for molecular imaging. In this study we labeled the anti–human …

RIT has become an attractive strategy in cancer treatment, but still faces important drawbacks
due to poor tumor penetration and undesirable pharmacokinetics of the targeting vehicles. …

Nanobodies (Nbs), the variable domains of camelid heavy chain-only antibodies, are a
promising class of therapeutics or in vivo imaging reagents entering the clinic. They possess …