User profiles for Nicholas Keat
 | Nicholas KeatInvicro Verified email at imanova.co.uk Cited by 2711 |
Artifacts in CT: recognition and avoidance
JF Barrett, N Keat - Radiographics, 2004 - pubs.rsna.org
Artifacts can seriously degrade the quality of computed tomographic (CT) images, sometimes
to the point of making them diagnostically unusable. To optimize image quality, it is …
to the point of making them diagnostically unusable. To optimize image quality, it is …
Clinical translation of a click-labeled 18F-octreotate radioligand for imaging neuroendocrine tumors
SR Dubash, N Keat, P Mapelli, F Twyman… - Journal of Nuclear …, 2016 - Soc Nuclear Med
We conducted the first-in-human study of 18 F-fluoroethyl triazole [Tyr 3 ] octreotate ( 18 F-FET-βAG-TOCA)
in patients with neuroendocrine tumors (NETs) to evaluate biodistribution, …
in patients with neuroendocrine tumors (NETs) to evaluate biodistribution, …
[HTML][HTML] PET image reconstruction using physical and mathematical modelling for time of flight PET-MR scanners in the STIR library
This work demonstrates how computational and physical modelling of the positron emission
tomography (PET) image acquisition process for a state-of-the-art integrated PET and …
tomography (PET) image acquisition process for a state-of-the-art integrated PET and …
A microdose PET study of the safety, immunogenicity, biodistribution, and radiation dosimetry of 18F-FB-A20FMDV2 for imaging the integrin αvβ6
N Keat, J Kenny, K Chen, M Onega… - Journal of nuclear …, 2018 - Soc Nuclear Med
The α v β 6 integrin is involved in the pathogenesis of cancer and fibrosis. A radiolabeled 20-amino-acid
α v β 6 -binding peptide, derived from the foot and mouth virus (…
α v β 6 -binding peptide, derived from the foot and mouth virus (…
Performance evaluation for CT-AEC (CT automatic exposure control) systems
…, R Sekine, N Niwa, M Terada, N Keat… - … Gijutsu Gakkai Zasshi, 2007 - europepmc.org
Although many current CT scanners incorporate CT-AEC, performance evaluation is not
standardized. This study evaluates the performance of the latest CT-AEC of each manufacturer …
standardized. This study evaluates the performance of the latest CT-AEC of each manufacturer …
[HTML][HTML] Clinical translation of 18F-fluoropivalate – a PET tracer for imaging short-chain fatty acid metabolism: safety, biodistribution, and dosimetry in fed and fasted …
SR Dubash, N Keat, K Kozlowski, C Barnes… - European Journal of …, 2020 - Springer
Background Fatty acids derived de novo or taken up from the extracellular space are an
essential source of nutrient for cell growth and proliferation. Radiopharmaceuticals including 11 …
essential source of nutrient for cell growth and proliferation. Radiopharmaceuticals including 11 …
[HTML][HTML] First evaluation of PET-based human biodistribution and radiation dosimetry of 11C-BU99008, a tracer for imaging the imidazoline2 binding site
Background We measured whole body distribution of 11 C-BU99008, a new PET biomarker
for non-invasive identification of the imidazoline 2 binding site. The purpose of this phase I …
for non-invasive identification of the imidazoline 2 binding site. The purpose of this phase I …
Somatostatin Receptor Imaging with [18F] FET-βAG-TOCA PET/CT and [68Ga] Ga-DOTA-Peptide PET/CT in Patients with Neuroendocrine Tumors: A Prospective …
…, B Pratap, S Azeem, M Huiban, N Keat… - Journal of Nuclear …, 2024 - Soc Nuclear Med
There is a clinical need for 18 F-labeled somatostatin analogs for the imaging of neuroendocrine
tumors (NET), given the limitations of using [ 68 Ga]Ga-DOTA-peptides, particularly with …
tumors (NET), given the limitations of using [ 68 Ga]Ga-DOTA-peptides, particularly with …
[HTML][HTML] Preclinical evaluation of [18F]FB-A20FMDV2 as a selective marker for measuring αVβ6 integrin occupancy using positron emission tomography in rodent …
Preclinical evaluation of [18F]FB-A20FMDV2 as a selective marker for measuring αVβ6
integrin occupancy using positron emission tomography in rodent lung | European Journal of …
integrin occupancy using positron emission tomography in rodent lung | European Journal of …
Biodistribution and Radiation Dosimetry of the Serotonin 5-HT6 Ligand [11C]GSK215083 Determined from Human Whole-Body PET
Purpose We measured the whole-body distribution of IV-injected [ 11 C]GSK215083, a new
5-HT 6 antagonist PET tracer, as a function of time in adult subjects, in order to determine the …
5-HT 6 antagonist PET tracer, as a function of time in adult subjects, in order to determine the …