PET of amino acid transport and metabolism may be more accurate than conventional
neuroimaging in differentiating recurrent gliomas from radiation-induced tissue changes. α- 11 C-…

Differentiating high-grade gliomas from solitary brain metastases is often difficult by
conventional magnetic resonance imaging (MRI); molecular imaging may facilitate such …

Background Although glioblastomas are heterogeneous brain-infiltrating tumors, their
treatment is mostly focused on the contrast-enhancing tumor mass. In this study, we combined …

Background Increased tryptophan metabolism via the kynurenine pathway (KP) is a key
mechanism of tumoral immune suppression in gliomas. However, details of tryptophan …

Objectives/Hypothesis External auditory canal (EAC) trauma, although rare, can have
significant long‐term adverse outcomes. This study aims to investigate the frequency, treatment, …

Background Previously, we demonstrated the high accuracy of alpha-[ 11 C]methyl-L-tryptophan
(AMT) PET for differentiating recurrent gliomas from radiation injury. The present study …

Background To assess gliomas using image-based estimation of cellularity, we utilized
isotropic diffusion spectrum imaging (IDSI) on clinically feasible diffusion tensor imaging (DTI) …

Amino acid PET is increasingly utilized for the detection of recurrent gliomas. Increased
amino acid uptake is often observed outside the contrast-enhancing brain tumor mass. In this …

A 42-year-old man presented with complaints of chronic daily right frontal headaches for the
past 9 months. His headaches were worse in the morning and throbbing in nature. The …

Tumor-treating fields (TTFields) therapy is a relatively new treatment approach for malignant
gliomas. We evaluated if amino acid PET can detect an objective metabolic response to …