PURPOSE: To investigate the utility of a monocrystalline iron oxide nanoparticle (MION) as
a contrast agent in magnetic resonance (MR) imaging of lymph nodes. MATERIALS AND …

Receptor-directed MR contrast agents are currently being designed to improve sensitivity and
specificity of MR imaging and to provide for functional MR imaging. In the current study we …

Gamma Imaging with Negatively Charge Modified Monoclonal Antibody: Modification with
Synthetic Polymers Page 1 tion of the radioactivity. High liver and kidney activities are observed …

Macromolecular carriers and liposomes were covalently coupled to monoclonal antibodies
against cardiac myosin heavy chain. Deferoxamine-modified polymers bound tightly with 67 …

PURPOSE: To investigate specific surface characteristics of magnetic contrast agents based
on a monocrystalline iron oxide nanoparticle (MION) that may determine their uptake and/or …

RESULTS The similarity of delivery of the two radiotracerswas confirmed by three observers
independently for each study from sequential acquisition images of the first (Fig. 4, top) and …

Monoclonal antimyosin Fab (AM-Fab) was radiolabeled with 111In via a new bifunctional
chelating agent, isothiocyanatobenzyl-DTPA (SCN-DTPA), and used to visualize acute …

Positively charged polymers have been shown to interact nonselectively with cells in vitro by
means of an electrostatic binding to a negatively charged cell surface. We reasoned that, if …

Background Cell surfaces and intercellular matrixes contain acidic residues, making them
negatively charged. Antibodies are basic, positively charged glycoproteins. Therefore the …

RATIONALE AND OBJECTIVES. The authors synthesized and tested a novel hydrogel
system proposed for use in extra-and intravascular radiologic interventions, such as …