Partial least squares analysis of neuroimaging data: applications and advances

AR McIntosh, NJ Lobaugh - Neuroimage, 2004 - Elsevier
Partial least squares (PLS) analysis has been used to characterize distributed signals
measured by neuroimaging methods like positron emission tomography (PET), functional …

Age-related decline in white matter tract integrity and cognitive performance: a DTI tractography and structural equation modeling study

AN Voineskos, TK Rajji, NJ Lobaugh, D Miranda… - Neurobiology of …, 2012 - Elsevier
Age-related decline in microstructural integrity of certain white matter tracts may explain
cognitive decline associated with normal aging. Whole brain tractography and a novel clustering …

A novel in vivo atlas of human hippocampal subfields using high-resolution 3 T magnetic resonance imaging

…, JC Pruessner, S Chavez, MM Schira, NJ Lobaugh… - Neuroimage, 2013 - Elsevier
The hippocampus is a neuroanatomical structure that has been widely studied in the context
of learning, memory, stress, and neurodegeneration. Neuroanatomically, the hippocampus …

Spatiotemporal analysis of experimental differences in event-related potential data with partial least squares

NJ Lobaugh, R West, AR McINTOSH - Psychophysiology, 2001 - cambridge.org
One challenge in the analysis of event-related potentials (ERPs) is to identify task-related
differences in scalp topography. The multivariate Partial Least Squares (PLS) analysis was …

Interactions of prefrontal cortex in relation to awareness in sensory learning

AR McIntosh, MN Rajah, NJ Lobaugh - Science, 1999 - science.org
In an associative learning paradigm, human subjects could be divided based on whether
they were aware that one tone predicted a visual event and another did not. Only aware …

A robust method for extraction and automatic segmentation of brain images

N Kovacevic, NJ Lobaugh, MJ Bronskill, B Levine… - Neuroimage, 2002 - Elsevier
A new protocol is introduced for brain extraction and automatic tissue segmentation of MR
images. For the brain extraction algorithm, proton density and T2-weighted images are used …

Derivation of high-resolution MRI atlases of the human cerebellum at 3 T and segmentation using multiple automatically generated templates

…, Y Shah, S Chavez, MM Schira, NJ Lobaugh… - Neuroimage, 2014 - Elsevier
The cerebellum has classically been linked to motor learning and coordination. However,
there is renewed interest in the role of the cerebellum in non-motor functions such as cognition …

The brain-derived neurotrophic factor Val66Met polymorphism and prediction of neural risk for Alzheimer disease

…, TK Rajji, D Miranda, NJ Lobaugh… - Archives of general …, 2011 - jamanetwork.com
Context The brain-derived neurotrophic factor (BDNF) Val66Met (rs6265) polymorphism
may predict the risk of Alzheimer disease (AD). However, genetic association studies of …

Diffusion tensor tractography findings in schizophrenia across the adult lifespan

AN Voineskos, NJ Lobaugh, S Bouix, TK Rajji… - Brain, 2010 - academic.oup.com
In healthy adult individuals, late life is a dynamic time of change with respect to the
microstructural integrity of white matter tracts. Yet, elderly individuals are generally excluded from …

Lesion Explorer: a comprehensive segmentation and parcellation package to obtain regional volumetrics for subcortical hyperintensities and intracranial tissue

J Ramirez, E Gibson, A Quddus, NJ Lobaugh… - Neuroimage, 2011 - Elsevier
Subcortical hyperintensities (SH) are a commonly observed phenomenon on MRI of the
aging brain (Kertesz et al., 1988). Conflicting behavioral, cognitive and pathological …