Objectives: To introduce guidelines for the conduct, reporting, and critical appraisal of meta-analyses
evaluating diagnostic tests and to apply these guidelines to recently published meta…

Breast cancer screening holds a prominent place in public health, health care delivery, policy,
and women's health care decisions. Several factors are driving shifts in how population‐…

Timely follow‐up for positive cancer screening results remains suboptimal, and the evidence
base to inform decisions on optimizing the timeliness of diagnostic testing is unclear. This …

Background Surgery for spinal stenosis is widely performed, but its effectiveness as compared
with nonsurgical treatment has not been shown in controlled trials. Methods Surgical …

ContextLumbar diskectomy is the most common surgical procedure performed for back and
leg symptoms in US patients, but the efficacy of the procedure relative to nonoperative care …

Objective. —To examine whether secular trends in risk factor levels and improvements in
treatment can account for the observed decline in coronary heart disease mortality in the …

Background Management of degenerative spondylolisthesis with spinal stenosis is
controversial. Surgery is widely used, but its effectiveness in comparison with that of nonsurgical …

ContextFor patients with lumbar disk herniation, the Spine Patient Outcomes Research Trial
(SPORT) randomized trial intent-to-treat analysis showed small but not statistically …

OBJECTIVES: To compare persons with and without hip fracture for subsequent mortality
and change in disability and nursing home (NH) use. DESIGN: Population‐based historical …

Background: The management of degenerative spondylolisthesis associated with spinal
stenosis remains controversial. Surgery is widely used and has recently been shown to be more …