Research in the area of pulmonary drug delivery has gathered momentum in the last several
years, with increased interest in using the lung as a means of delivering drugs systemically. …

After intravenous injection, particles larger than red blood cells will be trapped in the first
capillary bed that they encounter. This is the principle of lung perfusion imaging in nuclear …

Chronic obstructive pulmonary disease is a leading cause of morbidity and mortality worldwide.
Exposure to cigarette smoke (CS) is a major risk factor for developing this chronic airflow …

As the end organ for the treatment of local diseases or as the route of administration for systemic
therapies, the lung is a very attractive target for drug delivery. It provides direct access to …

Chronic lung disease is a major worldwide health concern but better tools are required to
understand the underlying pathologies. Ventilation/perfusion (V/Q) single photon emission …

Objective: Antidepressants are commonly used drugs with potential for numerous drug
interactions. This study aims to systematically review the literature on drug interactions with …

Preclinical imaging allows pulmonary researchers to study lung disease and pulmonary
drug delivery noninvasively and longitudinally in small animals. However, anatomically …

Many women are unable to quit smoking during pregnancy and therefore are prescribed
drugs, including nicotine (nicotine replacement therapy [NRT]), to aid with smoking cessation. …

Formation of pulmonary tertiary immune structures is a characteristic feature of advanced
COPD. In the current study, we investigated the mechanisms of tertiary lymphoid tissue (TLT) …

Asthma is functionally characterized by increased airway sensitivity and reactivity. Multiple
mechanisms are believed to underlie these functional disorders, including impairment of …