Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti–carcinoembryonic antigen single-chain Fv-Fc antibody fragments

…, T Olafsen, DM Crow, G Sundaresan, M Subbarayan… - Cancer research, 2005 - AACR
Antibody fragments are recognized as promising vehicles for delivery of imaging and therapeutic
agents to tumor sites in vivo. The serum persistence of IgG1 and fragments with intact …

Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model

S Gupta, VM Adhami, M Subbarayan, GT MacLennan… - Cancer research, 2004 - AACR
Epidemiological studies and clinical observations suggest that nonsteroidal anti-inflammatory
drugs and certain selective cyclooxygenase (COX)-2 inhibitors may reduce the relative …

64Cu-Labeled Alpha-Melanocyte-Stimulating Hormone Analog for MicroPET Imaging of Melanocortin 1 Receptor Expression

Z Cheng, Z Xiong, M Subbarayan, X Chen… - Bioconjugate …, 2007 - ACS Publications
The alpha-melanocyte-stimulating hormone (α-MSH) receptor (melanocortin type 1 receptor,
or MC1R) plays an important role in the development and growth of melanoma cells. It was …

PET of malignant melanoma using 18F-labeled metallopeptides

…, Z Liu, Z Miao, H Liu, M Subbarayan… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Melanocortin type 1 receptor (MC1R), also known as α-melanocyte–stimulating hormone (α-MSH)
receptor, is an attractive molecular target for melanoma imaging and therapy. An 18 F-…

Semiautomated Radiosynthesis and Biological Evaluation of [18F]FEAU: A Novel PET Imaging Agent for HSV1-tk/sr39tk Reporter Gene Expression

FT Chin, M Namavari, J Levi, M Subbarayan… - Molecular Imaging and …, 2008 - Springer
2′-Deoxy-2′-[ 18 F]fluoro-5-ethyl-1-β-d-arabinofuranosyluracil ([ 18 F]FEAU) is a promising
radiolabeled nucleoside designed to monitor Herpes Simplex Virus Type 1 thymidine …

A simplified method for preparation of 99mTc-annexin V and its biologic evaluation for in vivo imaging of apoptosis after photodynamic therapy

M Subbarayan, UO Häfeli, DK Feyes… - Journal of Nuclear …, 2003 - Soc Nuclear Med
Apoptosis is the likely mechanism behind the effects of chemotherapeutic and radiation
treatments, rejection of organ transplants, and cell death due to hypoxic-ischemic injury. A …

Reproducibility of 3′-deoxy-3′-18F-fluorothymidine microPET studies in tumor xenografts in mice

JR Tseng, M Dandekar, M Subbarayan… - Journal of nuclear …, 2005 - Soc Nuclear Med
3′-Deoxy-3′- 18 F-fluorothymidine ( 18 F-FLT) has been used to image tumor proliferation
in preclinical and clinical studies. Serial microPET studies may be useful for monitoring …

Water-soluble 99mTc-labeled dendritic novel porphyrins tumor imaging and diagnosis

M Subbarayan, SJ Shetty, TS Srivastava… - Biochemical and …, 2001 - Elsevier
We have synthesized two water soluble dendritic porphyrins, termed DP1 and DP2 and
have successfully radiolabeled them with 99m Tc. These 99m Tc-labeled porphyrins were …

Synthesis of (4‐[18F]fluorophenyl)triphenylphosphonium as a potential imaging agent for mitochondrial dysfunction

Z Cheng, M Subbarayan, X Chen… - Journal of Labelled …, 2005 - Wiley Online Library
Synthesis of (4â•’[<sup>18</sup>F]fluorophenyl)triphenylphosphonium as a potential
imaging agent for mitochondr Page 1 JOURNAL OF LABELLED COMPOUNDS AND …

Evaluation studies of technetium-99m-porphyrin (T3, 4BCPP) for tumor imaging

M Subbarayan, SJ Shetty, TS Srivastava… - Journal of Porphyrins …, 2001 - World Scientific
A water-soluble porphyrin, 5,10,15,20-tetrakis[3,4-bis(carboxymethyleneoxy)phenyl]
porphyrin (T3,4BCPP), was successfully labeled with 99 m Tc and biodistribution studies were …