Objective The presence of antibodies against cyclic citrullinated peptides has been demonstrated
to precede the onset of symptoms of rheumatoid arthritis (RA) by several years. The …

Objectives We explored the effects of B-cell directed therapy in subjects at risk of developing
autoantibodypositive rheumatoid arthritis (RA), who never experienced inflammatory …

Objective To investigate the role of genetic and environmental factors in the development of
anticitrullinated protein antibodies (ACPA) and ACPA-positive rheumatoid arthritis (RA) in a …

Objective Antibodies against posttranslationally modified proteins are a hallmark of rheumatoid
arthritis ( RA ), but the emergence and pathogenicity of these autoantibodies are still …

Objective Anti–citrullinated protein antibodies (ACPAs) are a hallmark of seropositive
rheumatoid arthritis (RA). Yet, the precise disease‐relevant autoantigens that are targeted by …

Introduction Overexpression of epidermal growth factor receptor (EGFR) is a prognostic and
predictive biomarker in a number of malignant tumours. Radionuclide molecular imaging of …

Introduction Autoantibodies directed against citrullinated proteins/peptides (ACPAs) are
highly specific and predictive for the development of rheumatoid arthritis (RA). Different …

Overexpression of the human epidermal growth factor receptor type 2 (HER2) in breast
carcinomas predicts response to trastuzumab therapy. Affibody molecules based on a …

Background Rheumatoid arthritis (RA) is classified as seropositive or seronegative,
depending on the presence/absence of rheumatoid factor (RF), primarily IgM RF, and/or anti-…

Objective Anti–citrullinated protein antibodies ( ACPA s) have proven highly useful as
biomarkers for rheumatoid arthritis ( RA ). However, composition and functionality of the …