[HTML][HTML] Homologous recombination and non‐homologous end‐joining pathways of DNA double‐strand break repair have overlapping roles in the maintenance of …

…, E Sonoda, C Morrison, M Hashimoto… - The EMBO …, 1998 - embopress.org
Eukaryotic cells repair DNA double‐strand breaks (DSBs) by at least two pathways, homologous
recombination (HR) and non‐homologous end‐joining (NHEJ). Rad54 participates in …

[HTML][HTML] Supranuclear melanin caps reduce ultraviolet induced DNA photoproducts in human epidermis

…, Y Yamashina, T Shirai, MW Hashimoto… - Journal of Investigative …, 1998 - Elsevier
Melanin can form supranuclear caps in human epidermis, suggesting that intracellular
melanin reduces ultraviolet transmission to underlying cell nuclei and inhibits the formation of …

RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1

…, T Tani, K Tokunaga, T Date, M Hashimoto… - Nucleic acids …, 2009 - academic.oup.com
Recruitment of RAD18 to stalled replication forks facilitates monoubiquitination of PCNA during
S-phase, promoting translesion synthesis at sites of UV irradiation-induced DNA damage…

The 2-deoxyribonolactone lesion produced in DNA by neocarzinostatin and other damaging agents forms cross-links with the base-excision repair enzyme …

M Hashimoto, MM Greenberg, YW Kow… - Journal of the …, 2001 - ACS Publications
The integrity of genetic information is safeguarded by families of DNA repair enzymes. Base-excision
repair (BER) enzymes incise base mispairs, altered nucleobases, and abasic sites. …

[HTML][HTML] Three-dimensional visualization of ultraviolet-induced DNA damage and its repair in human cell nuclei

…, Y Yamashina, T Shirai, MW Hashimoto… - Journal of investigative …, 1998 - Elsevier
The two major forms of DNA damage produced by 254 nm UV light are cyclobutane pyrimidine
dimer (CPD) and (6–4) photoproduct (6–4PP). Both photolesions are repaired in normal …

Depletion of RNA-binding protein RBM8A (Y14) causes cell cycle deficiency and apoptosis in human cells

…, T Tatsuno, M Hashimoto… - Experimental …, 2013 - journals.sagepub.com
RBM8A (Y14) contains an RNA-binding motif and forms a tight heterodimer with Magoh. The
heterodimer is known to be a member of the exon junction complex that forms on mRNA …

Cross-linking of 2-deoxyribonolactone and its β-elimination product by base excision repair enzymes

KM Kroeger, M Hashimoto, YW Kow… - Biochemistry, 2003 - ACS Publications
2-Deoxyribonolactone (3) is produced in DNA as a result of reaction with a variety of DNA
damaging agents. The lesion undergoes β-elimination to form a second metastable …

[HTML][HTML] Aquarius is required for proper CtIP expression and homologous recombination repair

R Sakasai, M Isono, M Wakasugi, M Hashimoto… - Scientific reports, 2017 - nature.com
Accumulating evidence indicates that transcription is closely related to DNA damage formation
and that the loss of RNA biogenesis factors causes genome instability. However, whether …

[HTML][HTML] Comparison of diagnostic performance of four software packages for phase dyssynchrony analysis in gated myocardial perfusion SPECT

…, H Yoneyama, T Shibutani, M Onoguchi, M Hashimoto… - EJNMMI research, 2017 - Springer
Background Phase analysis of gated myocardial perfusion single-photon emission computed
tomography (SPECT) for assessment of left ventricular (LV) dyssynchrony was investigated …

Prospective trial of radiotherapy for patients 80 years of age or older with squamous cell carcinoma of the thoracic esophagus

…, Y Tamura, S Hirota, N Fuwa, M Hashimoto… - International Journal of …, 2006 - Elsevier
Purpose: To assess the safety and efficacy of external beam radiotherapy for elderly patients
with esophageal cancer. Methods and Materials: A trial testing external beam radiotherapy (…