M. Yamaoka, S. Yamaguchi, T. Suzuki, M. Okuyama, J. Nitobe, N. Nakamura, Y. Mitsui and H.
Tomoike. Apoptosis in Rat Cardiac Myocytes Induced by Fas Ligand: Priming for Fas-…

Proinflammatory cytokines, ie, tumor necrosis factor-alpha (TNFα), participate in the
development and the progression of congestive heart failure (CHF). On the other hand, an anti-…

Fas ligand (FasL) is a 40-kD type II transmembrane protein that is homologous to tumor
necrosis factor-(TNF-). 1 FasL induces apoptosis by binding to its membrane receptor Fas (CD95…

Fas, also called APO-1, is a type I membrane protein of 45 kDa which is expressed in various
tissues and cells including the thymus, liver, ovary, lung, and heart. 1–3 Fas is a member of …

Background— Neovascularization is potentially important for the treatment of ischemic heart
and limb disease. We reported that reactive oxygen species (ROS) derived from gp91 phox (…

Endothelial cell (EC) proliferation and migration are important for reendothelialization and
angiogenesis. We have demonstrated that reactive oxygen species (ROS) derived from the …

Eight years have passed since the publication of the only guideline on cardiac rehabilitation
(CR) in Japan,“Guidelines for rehabilitation in patients with cardiovascular disease (JCS …

Background It has been known that Tc 99m sestamibi/iodine 123
betamethyliodophenylpentadecanoic (123 I-BMIPP)(sestamibi/BMIPP) mismatch is an indicator of …

Background Although gait speed and six-minute walk distance are used to assess functional
capacity in older patients with cardiovascular disease, their prognostic capabilities have not …

In atherosclerosis patients, vascular endothelial dysfunction is commonly observed alongside
damage of the vascular endothelial glycocalyx, an extracellular matrix bound to and …