Background CSF and PET biomarkers of amyloid β and tau accurately detect Alzheimer's
disease pathology, but the invasiveness, high cost, and poor availability of these detection …

Compelling experimental evidence suggests that microglial activation is involved in the spread
of tau tangles over the neocortex in Alzheimer’s disease (AD). We tested the hypothesis …

… Author links open overlay panel Maria Ironside 1 2 , Poornima Kumar 1 2 , Min-Su Kang
1 , Diego A Pizzagalli 1 2 … SU Maier, AB Makwana, TA Hare …

Background 18 F-THK5351 is a quinoline-derived tau imaging agent with high affinity to paired
helical filaments (PHF). However, high levels of 18 F-THK5351 retention in brain regions …

A skin adhesive patch is the most fundamental and widely used medical device for diverse
health‐care purposes. Conventional skin adhesive patches have been mainly utilized for …

To the Editor: Highly pathogenic avian influenza (HPAI) viruses have caused considerable
economic losses to the poultry industry and poses potential threats to animal and human …

Inadequate pain management after total knee arthroplasty (TKA) impedes recovery, increases
the risk of postoperative complications, and results in patient dissatisfaction. Although the …

Braak stages of tau neurofibrillary tangle accumulation have been incorporated in the
criteria for the neuropathological diagnosis of Alzheimer’s disease. It is expected that Braak …

Importance Apolipoprotein E ε4 (APOEε4) is the single most important genetic risk factor for
Alzheimer disease. WhileAPOEε4is associated with increased amyloid-β burden, its …

Animal studies suggest that the apolipoprotein E ε4 (APOEε4) allele is a culprit of early
microglial activation in Alzheimer’s disease (AD). Here, we tested the association between …