Surfactant protein B (SP-B) is an 8.7-kDa, hydrophobic protein that enhances the spreading
and stability of surfactant phospholipids in the alveolus. To further assess the role of SP-B in …

Surfactant protein D (SP-D) is a 43-kDa member of the collectin family of collagenous lectin
domain-containing proteins that is expressed in epithelial cells of the lung. The SP-D gene …

We conducted a randomized, double-blind, controlled trial to determine whether vitamin A
supplementation from early postnatal life could reduce the morbidity associated with …

Foxa1 and Foxa2 are closely related family members of the Foxa group of transcription
factors that are coexpressed in subsets of respiratory epithelial cells throughout lung …

The airways are lined by several distinct epithelial cells that play unique roles in pulmonary
homeostasis; however, the mechanisms controlling their differentiation in health and disease …

As a result of randomized assignment, 15 preterm infants weighing 1,500 gm or less at birth
and whohad a symptomatic PDA were treated according to a medical management protocol, …

SP-C-deficient (SP-C −/−) mice developed a severe pulmonary disorder associated with
emphysema, monocytic infiltrates, epithelial cell dysplasia, and atypical accumulations of …

The human gene encoding thyroid transcription factor-1 (TTF-1), a homeodomain-containing
nuclear transcription protein of the Nkx2 gene family, was isolated and characterized. …

We assessed the immunohistochemical localization of thyroid transcription factor-1 (TTF-1)
in the lungs of 24 human fetuses (11-23 weeks), three infants without pulmonary pathology (…

An activated form of β-catenin [Catnb Δ(ex3) ] was expressed in respiratory epithelial cells
of the developing lung. Although morphogenesis was not altered at birth, air space …