Background Patients with human papillomavirus–related oropharyngeal cancers have
excellent outcomes but experience clinically significant toxicities when treated with standard …

PURPOSE Desmoplastic small round cell tumor (DSRCT), a rare sarcoma of adolescents/young
adults primarily involving the peritoneum, has a long-term survival of< 20% despite …

Purpose: We performed a first-in-human clinical trial. The aim of this study was to determine
safety and feasibility of PET imaging with 18 F-PARPi in patients with head and neck cancer. …

Background and purpose Hypoxia is a known prognostic factor in head and neck cancer.
Hypoxia imaging PET radiotracers such as 18 F-FMISO are promising but not widely available. …

In this study, we investigate the use of imaging feature-based outcomes research ('radiomics')
combined with machine learning techniques to develop robust predictive models for the …

Diseases are a manifestation of how thousands of proteins interact. In several diseases,
such as cancer and Alzheimer’s disease, proteome-wide disturbances in protein-protein …

Tumor hypoxia and perfusion are independent prognostic indicators of patient outcome. We
developed the methodology for and investigated the utility of multiparametric imaging of …

Radiation dose estimations are key for optimizing therapies. We studied the role of 124 I-omburtamab
(8H9) given intraventricularly in assessing the distribution and radiation doses …

Purpose There is growing recognition that biologic features of the tumor microenvironment
affect the response to cancer therapies and the outcome of cancer patients. In head and neck …

Background Brain cancer incidence and mortality rates are greater in males. Understanding
the molecular mechanisms that underlie those sex differences could improve treatment …