The gut microbiota influences blood-brain barrier permeability in mice
…, C Kowal, F Anuar, A Abbaspour, M Tóth… - Science translational …, 2014 - science.org
Pivotal to brain development and function is an intact blood-brain barrier (BBB), which acts
as a gatekeeper to control the passage and exchange of molecules and nutrients between …
as a gatekeeper to control the passage and exchange of molecules and nutrients between …
Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior
…, A Ieraci, T Khan, CJ Siao, DG Herrera, M Toth… - science, 2006 - science.org
A common single-nucleotide polymorphism in the brain-derived neurotrophic factor (BDNF)
gene, a methionine (Met) substitution for valine (Val) at codon 66 (Val66Met), is associated …
gene, a methionine (Met) substitution for valine (Val) at codon 66 (Val66Met), is associated …
Increased anxiety of mice lacking the serotonin1A receptor
Brain serotonin (5-HT) has been implicated in a number of physiological processes and
pathological conditions. These effects are mediated by at least 14 different 5-HT receptors. We …
pathological conditions. These effects are mediated by at least 14 different 5-HT receptors. We …
Cortical 5-HT2A Receptor Signaling Modulates Anxiety-Like Behaviors in Mice
Serotonin [5-hydroxytryptamine (5-HT)] neurotransmission in the central nervous system
modulates depression and anxiety-related behaviors in humans and rodents, but the …
modulates depression and anxiety-related behaviors in humans and rodents, but the …
Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin1A receptors
…, RJ Fenster, BS McEwen, M Tóth - Proceedings of the …, 2000 - National Acad Sciences
The hippocampus is a major limbic target of the brainstem serotonergic neurons that
modulate fear, anxiety, and learning through postsynaptic serotonin 1A receptors (5-HT 1A …
modulate fear, anxiety, and learning through postsynaptic serotonin 1A receptors (5-HT 1A …
Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility
…, S Pikkarainen, J Piuhola, J Rysä, M Tóth… - Circulation …, 2002 - Am Heart Assoc
The orphan receptor APJ and its recently identified endogenous ligand, apelin, exhibit high
levels of mRNA expression in the heart. However, the functional importance of apelin in the …
levels of mRNA expression in the heart. However, the functional importance of apelin in the …
Co-expression and In Vivo Interaction of Serotonin1A and Serotonin2A Receptors in Pyramidal Neurons of Prefrontal Cortex
The prefrontal cortex plays a key role in the control of higher brain functions and is involved
in the pathophysiology and treatment of schizophrenia. Here we report that ∼60% of the …
in the pathophysiology and treatment of schizophrenia. Here we report that ∼60% of the …
The European Registry on Cushing's syndrome: 2-year experience. Baseline demographic and clinical characteristics
Objective The European Registry on Cushing's syndrome (ERCUSYN) is designed to
collect prospective and follow-up data at EU level on Cushing's syndrome (CS). Design and …
collect prospective and follow-up data at EU level on Cushing's syndrome (CS). Design and …
Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure
…, Z Lakó-Futó, R dechatel, H Ruskoaho, M Tóth - Biochemical and …, 2003 - Elsevier
The orphan receptor APJ and its recently identified endogenous ligand, apelin, are expressed
in the heart. However, their importance in the human cardiovascular system is not known. …
in the heart. However, their importance in the human cardiovascular system is not known. …
Fragile X mice develop sensory hyperreactivity to auditory stimuli
L Chen, M Toth - Neuroscience, 2001 - Elsevier
Fragile X syndrome is the most prevalent cause of mental retardation. It is usually caused by
the transcriptional inactivation of the FMR-1 gene. Although the cognitive defect is the most …
the transcriptional inactivation of the FMR-1 gene. Although the cognitive defect is the most …