The cardioprotective properties of carvedilol (a vasodilating β‐adrenoceptor blocking agent)
were studied in a rat model of dilated cardiomyopathy induced by autoimmune myocarditis. …

Background— Although immunosuppressive therapy for myocarditis has attracted a great
deal of attention, its effectiveness is controversial. Interleukin (IL)-10 has a variety of …

The hereditary form comprises ≈1/5 of patients with dilated cardiomyopathy (DCM) and is a
major cause of advanced heart failure. Medical and socioeconomic settings require novel …

Excessive NO produced by an inducible NO synthase (iNOS) has been implicated in many
types of immune-associated disorders of the cardiovascular system, but it remains to be …

Experimental autoimmune myocarditis (EAM) in rats is an animal model of human giant cell
myocarditis and postmyocarditis dilated cardiomyopathy. As the heart consumes large …

Advanced heart failure (HF) is the leading cause of death in developed countries. The
mechanism underlying the progression of cardiac dysfunction needs to be clarified to establish …

The precise mechanism of the progression of advanced heart failure is unknown. We
assessed a new scheme in two heart failure models: (I) congenital dilated cardiomyopathy (DCM) …

The effects of inhibitors of cytochrome P450 on myocardial regional ischemia–reperfusion
injury were examined in rats. Ischemia–reperfusion injury was evoked by ligation of the left …

Erythropoietin (EPO) has been known to have cytoprotective effects on several types of
tissues, presumably through modulation of apoptosis and inflammation. The effect of EPO on …

Background— Interleukin-1 (IL-1) is a powerful and important cytokine in myocarditis. The
purpose of this study was to evaluate the effect and possible mechanism of hydrodynamics-…