PURPOSE Clinical outcomes of patients with CNS lymphomas (CNSLs) are remarkably
heterogeneous, yet identification of patients at high risk for treatment failure is challenging. …

Background Systemic cancer spread is preceded by the establishment of a permissive
microenvironment in the target tissue of metastasis-the premetastatic niche. As crucial players in …

Simple Summary Access to molecular cancer treatments outside of clinical trials is limited
and the benefit of molecular-guided, individualized patient care in patients with cancer …

Tumors recruit and reprogram immune cells to support tumor development and spread, the
most prominent among them being of monocytic origin such as tumor-associated …

Tumor development and growth, as well as metastatic spread, are strongly influenced by
various, mostly innate, immune cells, which are recruited to the tumor site and driven to …

Simple Summary The term “clinically relevant prostate carcinoma” (csPCa) is used to differentiate
the types of prostate carcinoma (PCa) that can lead to the death of the affected patient …

Locoregional recurrence of breast cancer poses significant clinical problems because of
frequent inoperability once the chest wall is involved. Early detection of recurrence by molecular …

Objectives Quantitative MRI techniques, such as diffusion microstructure imaging (DMI), are
increasingly applied for advanced tissue characterization. We determined its value in rotator …

Background Central nervous system lymphomas (CNSL) display remarkable clinical
heterogeneity, yet accurate prediction of outcomes remains challenging. The IPCG criteria are …

Das Zervixkarzinom ist weltweit noch immer das vierthäufigste Malignom der Frau und hat
eine hohe Mortalitätsrate. Die Prognose sowie die Therapie hängen maßgeblich von der …