Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

…, WJ Jagust, RC Petersen, MW Weiner… - The lancet …, 2013 - thelancet.com
In 2010, we put forward a hypothetical model of the major biomarkers of Alzheimer's disease
(AD). The model was received with interest because we described the temporal evolution of …

The Alzheimer's disease neuroimaging initiative (ADNI): MRI methods

…, G Glover, J Mugler, MW Weiner - Journal of Magnetic …, 2008 - Wiley Online Library
The Alzheimer's Disease Neuroimaging Initiative (ADNI) is a longitudinal multisite observational
study of healthy elders, mild cognitive impairment (MCI), and Alzheimer's disease. …

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

…, WJ Jagust, LM Shaw, PS Aisen, MW Weiner… - The Lancet …, 2010 - thelancet.com
Currently available evidence strongly supports the position that the initiating event in
Alzheimer's disease (AD) is related to abnormal processing of β-amyloid (Aβ) peptide, ultimately …

Alzheimer's disease Neuroimaging Initiative (ADNI) clinical characterization

…, LM Shaw, AW Toga, JQ Trojanowski, MW Weiner - Neurology, 2010 - AAN Enterprises
Background: Neuroimaging measures and chemical biomarkers may be important indices
of clinical progression in normal aging and mild cognitive impairment (MCI) and need to be …

Cognition and anatomy in three variants of primary progressive aphasia

…, HJ Rosen, JK Johnson, MW Weiner… - Annals of Neurology …, 2004 - Wiley Online Library
We performed a comprehensive cognitive, neuroimaging, and genetic study of 31 patients
with primary progressive aphasia (PPA), a decline in language functions that remains isolated …

Ways toward an early diagnosis in Alzheimer's disease: the Alzheimer's Disease Neuroimaging Initiative (ADNI)

SG Mueller, MW Weiner, LJ Thal, RC Petersen… - Alzheimer's & …, 2005 - Elsevier
With the increasing life expectancy in developed countries, the incidence of Alzheimer’s
disease (AD) and thus its socioeconomic impact are growing. Increasing knowledge over the …

The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception

MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2013 - Elsevier
The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing, longitudinal, multicenter
study designed to develop clinical, imaging, genetic, and biochemical biomarkers for the …

The Alzheimer's disease neuroimaging initiative

SG Mueller, MW Weiner, LJ Thal… - Neuroimaging …, 2005 - neuroimaging.theclinics.com
With increasing life expectancy in developed countries, diseases typically associated with old
age are becoming more frequent and, thus, increasingly gain in socioeconomic importance…

Identification of common variants associated with human hippocampal and intracranial volumes

…, AW Toga, DJ Veltman, H Walter, MW Weiner - Nature …, 2012 - nature.com
Identifying genetic variants influencing human brain structures may reveal new biological
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …

Clinical Core of the Alzheimer's Disease Neuroimaging Initiative: progress and plans

…, JC Morris, RC Green, MW Weiner… - Alzheimer's & …, 2010 - Wiley Online Library
The Clinical Core of the Alzheimer's Disease Neuroimaging Initiative (ADNI) has provided
clinical, operational, and data management support to ADNI since its inception. This article …