From bacteria to mammalian cells, damaged DNA is sensed and targeted by DNA repair
pathways. In eukaryotes, kinases play a central role in coordinating the DNA damage response. …

Cell size is tightly controlled in healthy tissues, but it is unclear how deviations in cell size
affect cell physiology. To address this, we measured how the cell's proteome changes with …

Multiple sclerosis (MS) is a common neurological disease in the Western hemisphere that
leads to neurological dysfunctions and frequently from its onset to cognitive impairment, which …

Phosphorylation is one of the most dynamic and widespread post‐translational modifications
regulating virtually every aspect of eukaryotic cell biology. Here, we assemble a dataset …

Purpose: Cognitive disorders are common in MS patients without any generally recommended
treatment. Recent brain imaging studies show considerable neuroplasticity for cognitive …

Posttranslational protein modification by ubiquitin (Ub) is a central eukaryotic mechanism
that regulates a plethora of physiological processes. Recent studies unveiled an …

Chronic alcohol abuse leads to cognitive deficits. The authors investigated whether a systematic
increase of interference in a 2-back working memory paradigm would lead to cognitive …

Increasing cell size drives changes to the proteome, which affects cell physiology. As cell size
increases, some proteins become more concentrated while others are diluted. As a result, …

This paper describes with typical examples the state of art. The list of examples includes the
problems of non-robust formulations and critical processes. The paper demonstrates the …

We combined diffusion tensor imaging (DTI) measures of the corpus callosum (CC) and the
superior longitudinal fascicle (SLF) with calculation of brain atrophy in 53 patients with …