Basic Clinical Radiobiology is a concise but comprehensive textbook setting out the essentials
of the science and clinical application of radiobiology for those seeking accreditation in …

Purpose: To retain cell viability, mammalian cells can increase damage repair in response
to excessive radiation-induced injury. The adaptive response to small radiation doses is an …

Marples, B., Wouters, BG, Collis, SJ, Chalmers, AJ and Joiner, MC Low-Dose Hyper-radiosensitivity:
A Consequence of Ineffective Cell Cycle Arrest of Radiation-Damaged G 2 -Phase …

… Bentzen a , Wolfgang Dörr b , Reinhard Gahbauer c , Roger W. Howell d , Michael C.
Joiner e , Bleddyn Jones f , Dan TL Jones g , Albert J. van der Kogel h , André Wambersie i , …

Major developments in radiotherapy fractionation have taken place during the past four decades
and continue to do so, and these have grown directly out of increasing understanding in …

As soon as relatively accurate dosimetry became available around 1910, it became clear
that the biological effect of a given physical dose of ionizing radiation depends on how this …

Despite numerous observations linking protracted exposure to low-dose (LD) radiation and
leukemia occurrence, the effects of LD irradiation on hematopoietic stem cells (HSCs) …

The maintenance of tissue size and therefore of tissue function in the normal renewal tissues
of the body depends upon the existence of a small number of primitive ‘stem cells’ – cells …

The response of cells to ionizing radiation is strongly dependent upon oxygen (Gray et al.,
1953; Wright and Howard-Flanders, 1957). This is illustrated in Fig. 15.1 for mammalian cells …

Objective: We have shown previously that pretreatment with genistein potentiated cell killing
induced by radiation in human PC-3 prostate carcinoma cell line in vitro. We tested this …