User profiles for Michael C. Chang
Michael C ChangGenentech, Inc. Verified email at gene.com Cited by 1328 |
Relationship of early hyperglycemia to mortality in trauma patients
…, PD Kilgo, JW Meredith, MC Chang - Journal of Trauma …, 2004 - journals.lww.com
Methods: The records of all patients admitted to the ICU over a 2-year period at a Level I
trauma center were reviewed for age, injury severity scores (ISS), admission Glasgow Coma …
trauma center were reviewed for age, injury severity scores (ISS), admission Glasgow Coma …
Diagnosis and initial management of blunt pancreatic trauma: guidelines from a multiinstitutional review
EL Bradley III, PR Young Jr, MC Chang, JE Allen… - Annals of …, 1998 - journals.lww.com
Objective The authors' objective was to resolve the current controversies surrounding the
diagnosis and management of blunt pancreatic trauma (BPT). Summary Background Data The …
diagnosis and management of blunt pancreatic trauma (BPT). Summary Background Data The …
Prospective evaluation of vacuum-assisted fascial closure after open abdomen: planned ventral hernia rate is substantially reduced
…, JW Meredith, JC Johnson, MC Chang - Annals of surgery, 2004 - journals.lww.com
Objective: The goal of this report is to examine the success of vacuum-assisted fascial
closure (VAFC) under a carefully applied protocol in abdominal closure after open abdomen. …
closure (VAFC) under a carefully applied protocol in abdominal closure after open abdomen. …
External fixation or arteriogram in bleeding pelvic fracture: initial therapy guided by markers of arterial hemorrhage
…, E Mansell, JW Meredith, MC Chang - Journal of Trauma …, 2003 - journals.lww.com
Background Bleeding pelvic fractures (BPF) carry mortality as high as 60%, yet controversy
remains over optimal initial management. Some base initial intervention on fracture pattern, …
remains over optimal initial management. Some base initial intervention on fracture pattern, …
The spectrum of blunt injury to the carotid artery: a multicenter perspective
…, MC Chang, GT Trevasani, C Aprahamian… - Journal of Trauma …, 1994 - journals.lww.com
The relative infrequency of blunt carotid artery trauma prompted a multicenter review to
determine the spectrum of injuries, treatment strategies, and neurologic outcome. During a six-…
determine the spectrum of injuries, treatment strategies, and neurologic outcome. During a six-…
Narp regulates homeostatic scaling of excitatory synapses on parvalbumin-expressing interneurons
Homeostatic synaptic scaling alters the strength of synapses to compensate for prolonged
changes in network activity and involves both excitatory and inhibitory neurons. The immediate…
changes in network activity and involves both excitatory and inhibitory neurons. The immediate…
[PDF][PDF] Complement C3 is activated in human AD brain and is required for neurodegeneration in mouse models of amyloidosis and tauopathy
Complement pathway overactivation can lead to neuronal damage in various neurological
diseases. Although Alzheimer's disease (AD) is characterized by β-amyloid plaques and tau …
diseases. Although Alzheimer's disease (AD) is characterized by β-amyloid plaques and tau …
Estimation of intra-abdominal pressure by bladder pressure measurement: validity and methodology
MA Fusco, RS Martin, MC Chang - Journal of Trauma and Acute …, 2001 - journals.lww.com
Background Increased intra-abdominal pressure (IAP) is an adverse complication seen in
critically ill, injured, and postoperative patients. IAP is estimated via the measurement of …
critically ill, injured, and postoperative patients. IAP is estimated via the measurement of …
[HTML][HTML] Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models
…, T Singh, J Klumperman, O Foreman, MC Chang… - Nature aging, 2022 - nature.com
Microglia and complement can mediate neurodegeneration in Alzheimer’s disease (AD). By
integrative multi-omics analysis, here we show that astrocytic and microglial proteins are …
integrative multi-omics analysis, here we show that astrocytic and microglial proteins are …
Late fascial closure in lieu of ventral hernia: the next step in open abdomen management
…, BJ Faler, JW Meredith, MC Chang - Journal of Trauma …, 2002 - journals.lww.com
Background The use of open abdomen techniques in damage control laparotomy and
abdominal compartment syndrome has led to development of several methods of temporary …
abdominal compartment syndrome has led to development of several methods of temporary …