[HTML][HTML] Positron emission tomography (PET) imaging with 18F-based radiotracers
MM Alauddin - American journal of nuclear medicine and …, 2012 - ncbi.nlm.nih.gov
Positron Emission Tomography (PET) is a nuclear medicine imaging technique that is widely
used in early detection and treatment follow up of many diseases, including cancer. This …
used in early detection and treatment follow up of many diseases, including cancer. This …
[HTML][HTML] A hybrid vector for ligand-directed tumor targeting and molecular imaging
…, M Trepel, CE Lilley, S Soghomonyan, MM Alauddin… - Cell, 2006 - cell.com
Merging tumor targeting and molecular-genetic imaging into an integrated platform is limited
by lack of strategies to enable systemic yet ligand-directed delivery and imaging of specific …
by lack of strategies to enable systemic yet ligand-directed delivery and imaging of specific …
Comparison of radiolabeled nucleoside probes (FIAU, FHBG, and FHPG) for PET imaging of HSV1-tk gene expression
…, T Akhurst, S Cai, J Balatoni, MM Alauddin… - Journal of Nuclear …, 2002 - Soc Nuclear Med
The efficacy of 3 radiolabeled probes of current interest for imaging herpes simplex virus
type 1 thymidine kinase (HSV1-tk) expression in vivo with PET, including 124 I- or 131 I-labeled …
type 1 thymidine kinase (HSV1-tk) expression in vivo with PET, including 124 I- or 131 I-labeled …
[HTML][HTML] Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma
…, X Liang, V Paolillo, MM Alauddin… - The Journal of …, 2011 - Am Soc Clin Investig
The management of CNS tumors is limited by the blood-brain barrier (BBB), a vascular interface
that restricts the passage of most molecules from the blood into the brain. Here we show …
that restricts the passage of most molecules from the blood into the brain. Here we show …
Synthesis and preliminary evaluation of 9-(4-[18F]-fluoro-3-hydroxymethylbutyl) guanine ([18F] FHBG): a new potential imaging agent for viral infection and gene …
MM Alauddin, PS Conti - Nuclear medicine and biology, 1998 - Elsevier
Synthesis and preliminary biological evaluation of 9-(4-[ 18 F]-fluoro-3-hydroxymethylbutyl)guanine
([ 18 F]FHBG) is reported. 9-(4-Hydroxy-3-hydroxymethylbutyl)-guanine (penciclovir) …
([ 18 F]FHBG) is reported. 9-(4-Hydroxy-3-hydroxymethylbutyl)-guanine (penciclovir) …
Design and construction of targeted AAVP vectors for mammalian cell transduction
…, S Soghomonyan, JG Gelovani, MM Alauddin… - Nature protocols, 2007 - nature.com
Bacteriophage (phage) evolved as bacterial viruses, but can be adapted to transduce
mammalian cells through ligand-directed targeting to a specific receptor. We have recently …
mammalian cells through ligand-directed targeting to a specific receptor. We have recently …
Molecular imaging of active mutant L858R EGF receptor (EGFR) kinase-expressing nonsmall cell lung carcinomas using PET/CT
…, V Krasnykh, W Tong, MM Alauddin… - Proceedings of the …, 2011 - National Acad Sciences
The importance of the EGF receptor (EGFR) signaling pathway in the development and
progression of nonsmall cell lung carcinomas (NSCLC) is widely recognized. Gene sequencing …
progression of nonsmall cell lung carcinomas (NSCLC) is widely recognized. Gene sequencing …
Human CD34+ Cells in Experimental Myocardial Infarction: Long-Term Survival, Sustained Functional Improvement, and Mechanism of Action
…, L Bidaut, S Soghomonyan, MM Alauddin… - Circulation …, 2010 - Am Heart Assoc
Rationale: Human CD34 + cells have been used in clinical trials for treatment of myocardial
infarction (MI). However, it is unknown how long the CD34 + cells persist in hearts, whether …
infarction (MI). However, it is unknown how long the CD34 + cells persist in hearts, whether …
The selective hypoxia inducible factor-1 inhibitor PX-478 provides in vivo radiosensitization through tumor stromal effects
…, A Volgin, S Soghomonyan, R Nishii, M Alauddin… - Molecular cancer …, 2009 - AACR
Hypoxia inducible factor-1 (HIF-1) promotes tumor cell adaptation to microenvironmental
stress. HIF-1 is up-regulated in irradiated tumors and serves as a promising target for …
stress. HIF-1 is up-regulated in irradiated tumors and serves as a promising target for …
Synthesis of 2′-fluoro-5-[11C]-methyl-1-β-d-arabinofuranosyluracil ([11C]-FMAU): A potential nucleoside analog for in vivo study of cellular proliferation with PET
PS Conti, MM Alauddin, JR Fissekis, B Schmall… - Nuclear medicine and …, 1995 - Elsevier
Rapid in vivo catabolism limits the use of currently available radiotracers used in tumor
proliferation studies with PET. This is manifested by the need to develop complex mathematical …
proliferation studies with PET. This is manifested by the need to develop complex mathematical …