The deposition of β-amyloid (Aβ) plaques in the parenchymal and cortical brain is accepted
as the main pathological hallmark of Alzheimer’s disease (AD). According to the amyloid …

In vivo imaging of β-amyloid plaques in the brain may lead to the early diagnosis of Alzheimer’s
disease (AD) and monitoring of the progression and effectiveness of treatment. In the …

The early noninvasive diagnosis of Alzheimer’s disease targeted β-amyloid (Aβ) plaques or
Tau tangles is a major challenge because of the coshared β-sheet structure of the target. In …

Two radiofluoro-pegylated phenylbenzoxazole derivatives, 4-(5-(2-(2-(2-[ 18 F]fluoroethoxy)ethoxy)ethoxy)benzo[d]oxazol-2-yl)-N-methylaniline
([ 18 F]24) and 4-(5-(2-(2-(2-[ 18 F]…

In this review, we have focused on the recent progress in metal complexes that are able to
bind to β-amyloid (Aβ) species. We have discussed various radioactive complexes of 99mTc, …

Alzheimer's disease (AD) is a debilitating neurodegenerative dementia that involves substantial
neuronal loss. Extracellular deposition of neurotoxic β-amyloid (Aβ) plaques in the brain …

The imaging of β-amyloid (Aβ) aggregates in the brain may lead to the early detection of
Alzheimer’s disease (AD) and monitoring of the progression and effectiveness of treatment. The …

A novel and efficient method for the synthesis of difluoroalkylated benzofuran, benzothiophene,
and indole derivatives via palladium-catalyzed aryldifluoroalkylation of 1,6-enynes with …

A series of fluoro-pegylated (FPEG) 2-pyridinylbenzoxazole and 2-pyridinylbenzothiazole
derivatives were synthesized and evaluated as novel β-amyloid (Aβ) imaging probes for PET. …

The deposition of β-amyloid (Aβ) plaques in the parenchymal and cortical brain is accepted
as the main pathological hallmark of Alzheimer’s disease (AD); however, early detection of …