Safety and tumor specificity of cetuximab-IRDye800 for surgical navigation in head and neck cancer

…, JM Warram, E De Boer, TK Chung, ML Korb… - Clinical Cancer …, 2015 - AACR
Purpose: Positive margins dominate clinical outcomes after surgical resections in most solid
cancer types, including head and neck squamous cell carcinoma. Unfortunately, surgeons …

[HTML][HTML] In Vivo Fluorescence Immunohistochemistry: Localization of Fluorescently Labeled Cetuximab in Squamous Cell Carcinomas

…, LS Moore, JS De Jong, TK Chung, ML Korb… - Scientific reports, 2015 - nature.com
Anti-EGFR (epidermal growth factor receptor) antibody based treatment strategies have
been successfully implemented in head and neck squamous cell carcinoma (HNSCC). …

Use of monoclonal antibody–IRDye800CW bioconjugates in the resection of breast cancer

ML Korb, YE Hartman, J Kovar, KR Zinn… - journal of surgical …, 2014 - Elsevier
Background Complete surgical resection of breast cancer is a powerful determinant of patient
outcome, and failure to achieve negative margins results in reoperation in between 30% …

Laparoscopic fluorescent visualization of the ureter with intravenous IRDye800CW

ML Korb, WK Huh, JD Boone, JM Warram… - Journal of minimally …, 2015 - Elsevier
… Author links open overlay panel Melissa L. Korb MD a , Warner K. Huh MD b , Jonathan D.
Boone MD b , Jason M. … Bland MD a , Eben L. Rosenthal MD c …

Characterizing the utility and limitations of repurposing an open-field optical imaging device for fluorescence-guided surgery in head and neck cancer patients

…, E De Boer, N Patel, AC Prince, ML Korb… - Journal of Nuclear …, 2017 - Soc Nuclear Med
The purpose of this study was to assess the potential of US Food and Drug Administration–cleared
devices designed for indocyanine green–based perfusion imaging to identify cancer-…

Photoimmunotherapy of residual disease after incomplete surgical resection in head and neck cancer models

…, JM Warram, MD Tucker, WR Carroll, ML Korb… - Cancer …, 2016 - Wiley Online Library
Antibody‐based photodynamic therapy, or photoimmunotherapy ( PIT ), is a novel, targeted
cancer therapy, which can serve as both a diagnostic and a therapeutic agent. The primary …

Understanding the value of both laparoscopic and robotic approaches compared to the open approach in colorectal surgery

…, JA Cannon, BA Singletary, ML Korb… - … & Advanced Surgical …, 2016 - liebertpub.com
Intro: Although the use of laparoscopy has significantly increased in colorectal procedures,
robotic surgery may enable additional cases to be performed using a minimally invasive …

Breast cancer imaging using the near-infrared fluorescent agent, CLR1502

ML Korb, JM Warram, J Grudzinski… - Molecular …, 2015 - journals.sagepub.com
Positive margins after breast conservation surgery represent a significant problem in the
treatment of breast cancer. The near-infrared fluorescence agent CLR1502 (Cellectar …

Dynamic contrast‐enhanced MRI evaluates the early response of human head and neck tumor xenografts following anti‐EMMPRIN therapy with cisplatin or irradiation

…, G Zhai, TK Chung, ML Korb… - Journal of Magnetic …, 2015 - Wiley Online Library
Purpose To assess the early therapeutic effects of anti‐EMMPRIN (extracellular matrix
metalloprotease inducer) antibody with/without cisplatin or X‐ray radiation in head and neck …

Adoption of preoperative oral antibiotics decreases surgical site infection for elective colorectal surgery

ML Korb, MT Hawn, BA Singletary… - The American …, 2014 - journals.sagepub.com
Surgical site infections (SSIs) are the most common health care-associated infection with 10
to 23 per cent of patients undergoing colon operations experiencing a postoperative SSI. 1 …