Bispecific and bifunctional monoclonal antibodies as second generation monoclonals,
produced by conventional chemical or somatic methods, have proved useful in the …

Tuberculosis (TB) is a major threat in global public health. The emergence of HIV and also
multi drug resistant (MDR) and extremely drug resistant (XDR)-TB poses a vital challenge to …

A novel class of 1-(4-methanesulfonylphenyl and 4-aminosulfonylphenyl)-5-[4-(1-difluoromethyl-1,2-dihydropyrid-2-one)]-3-trifluoromethyl-1H-pyrazole
hybrid cyclooxygenase-2 (COX-2…

This work investigates the formulation and in vivo efficacy of dendritic cell (DC) targeted
plasmid DNA loaded biotinylated chitosan nanoparticles for nasal immunization against …

ABSTRACT-This review highlights the advantages and current status of plant-derived vaccine
development with special reference to the dengue virus. There are numerous problems …

A new group of hybrid nitric oxide (NO) releasing anti-inflammatory (AI) coxib prodrugs (NO-coxibs)
wherein the para-tolyl moiety present in celecoxib was replaced by a N-(4-…

In this study, we demonstrate a simple strategy for enhanced immune response using a two-component
dendritic cell (DC) targeted antigen delivery system. One component consists of …

The emergence of severe acute respiratory syndrome (SARS) resulted in several outbreaks
worldwide. Early tests for diagnosis were not always conclusive in identifying a SARS …

Ebola virus (EBOV) causes hemorrhagic fever in humans and nonhuman primates with up
to 90% mortality rate. In this study, Ebola virus like particles (EVLPs) and the aglycosyl …

Aims This study examined the functional role of B-type natriuretic peptide (BNP) in
epoxyeicosatrienoic acid (EET)-mediated cardioprotection in mice with targeted disruption of the sEH …