The considerable investment in silicon technology has rarely addressed device use in harsh
environments such as high temperatures, aggressive media, and radiation exposure. A …

Defective regulation of platelet activation/aggregation is a predominant cause for arterial
thrombosis, the major complication of atherosclerosis triggering myocardial infarction and stroke…

Signalling by cGMP‐dependent protein kinase type I (cGKI) relaxes various smooth muscles
modulating thereby vascular tone and gastrointestinal motility. cGKI‐dependent relaxation …

PURPOSE: To define prognostic factors for response and long-term outcome for a wide
spectrum of osteosarcomas, extending well beyond those of the typical young patient with …

Different calcium signals in the endothelium and smooth muscle target different types of Ca
2+ -sensitive K + channels to modulate vascular function. These differential calcium signals …

OBJECTIVE Brown adipose tissue (BAT) regulates energy homeostasis and fat mass in
mammals and newborns and, most likely, in adult humans. Because BAT activity and BAT mass …

BK large conductance voltage- and calcium-activated potassium channels respond to
elevations in intracellular calcium and membrane potential depolarization, braking excitability of …

Changes in intracellular Ca 2+ are central to the function of smooth muscle, which lines the
walls of all hollow organs. These changes take a variety of forms, from sustained, cell-wide …

This study aims to identify the potential mechanisms by which perivascular adipose tissue (PVAT)
reduces tone in small arteries. Small mesenteric arteries from wild-type and large-…

Penile erection is dependent on the nitric oxide (NO)/cGMP‐dependent protein kinase I (PKGI)
pathway. One important target of PKGI in smooth muscle is the large‐conductance, …