CB1 cannabinoid receptors and on-demand defense against excitotoxicity

…, S Goodenough, K Monory, H Hermann, M Eder… - Science, 2003 - science.org
Abnormally high spiking activity can damage neurons. Signaling systems to protect neurons
from the consequences of abnormal discharge activity have been postulated. We generated …

[HTML][HTML] The diagnostic value of PET/CT imaging with the 68Ga-labelled PSMA ligand HBED-CC in the diagnosis of recurrent prostate cancer

…, FL Giesel, T Holland-Letz, HG Linhart, M Eder… - European journal of …, 2015 - Springer
Purpose Since the introduction of positron emission tomography (PET) imaging with 68 Ga-PSMA-HBED-CC
(= 68 Ga-DKFZ-PSMA-11), this method has been regarded as a significant …

68Ga-Complex Lipophilicity and the Targeting Property of a Urea-Based PSMA Inhibitor for PET Imaging

M Eder, M Schäfer, U Bauder-Wüst… - Bioconjugate …, 2012 - ACS Publications
Urea-based inhibitors of the prostate-specific membrane antigen (PSMA) represent low-molecular-weight
pepidomimetics showing the ability to image PSMA-expressing prostate tumors…

PSMA-targeted radionuclide therapy of metastatic castration-resistant prostate cancer with 177Lu-labeled PSMA-617

…, A Afshar-Oromieh, W Mier, M Eder… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) is an excellent target for radionuclide therapy
of metastasized castration-resistant prostate cancer (mCRPC). Besides high affinity and long …

Preclinical evaluation of a tailor-made DOTA-conjugated PSMA inhibitor with optimized linker moiety for imaging and endoradiotherapy of prostate cancer

…, W Mier, U Haberkorn, K Kopka, M Eder - Journal of Nuclear …, 2015 - Soc Nuclear Med
Despite many advances in the past years, the treatment of metastatic prostate cancer still
remains challenging. In recent years, prostate-specific membrane antigen (PSMA) inhibitors …

The theranostic PSMA ligand PSMA-617 in the diagnosis of prostate cancer by PET/CT: biodistribution in humans, radiation dosimetry, and first evaluation of tumor …

…, C Kratochwil, M Benesova, M Eder… - Journal of Nuclear …, 2015 - Soc Nuclear Med
PET imaging with the prostate-specific membrane antigen (PSMA)–targeted radioligand 68
Ga-PSMA-11 is regarded as a significant step forward in the diagnosis of prostate cancer (…

[177Lu]Lutetium-labelled PSMA ligand-induced remission in a patient with metastatic prostate cancer

C Kratochwil, FL Giesel, M Eder… - European Journal of …, 2015 - Springer
The prostate-specific membrane antigen (PSMA) shows intense overexpression in the
majority of prostate cancers (PCa)[1]. A Glu-urea-Lys motif has been found to bind with high …

Ultramicroscopy: three-dimensional visualization of neuronal networks in the whole mouse brain

…, CP Mauch, K Deininger, JM Deussing, M Eder… - Nature …, 2007 - nature.com
Visualizing entire neuronal networks for analysis in the intact brain has been impossible up
to now. Techniques like computer tomography or magnetic resonance imaging (MRI) do not …

[HTML][HTML] Comparison of PET imaging with a 68Ga-labelled PSMA ligand and 18F-choline-based PET/CT for the diagnosis of recurrent prostate cancer

…, CM Zechmann, A Malcher, M Eder… - European journal of …, 2014 - Springer
Purpose Positron emission tomography (PET) with choline tracers has found widespread use
for the diagnosis of prostate cancer (PC). However, choline metabolism is not increased in …

[PDF][PDF] The endocannabinoid system controls key epileptogenic circuits in the hippocampus

K Monory, F Massa, M Egertová, M Eder, H Blaudzun… - Neuron, 2006 - cell.com
Balanced control of neuronal activity is central in maintaining function and viability of neuronal
circuits. The endocannabinoid system tightly controls neuronal excitability. Here, we show …