Serial troponin for early detection of nivolumab cardiotoxicity in advanced non‐small cell lung cancer patients
Background Rare cases of severe myocarditis are reported during treatment with nivolumab.
Troponin, a biomarker of cardiac damage, is a key component of the diagnostic workup of …
Troponin, a biomarker of cardiac damage, is a key component of the diagnostic workup of …
Doxorubicin effect on myocardial metabolism as a prerequisite for subsequent development of cardiac toxicity: a translational 18F-FDG PET/CT observation
…, F Fiz, S Morbelli, M Sarocchi… - Journal of Nuclear …, 2017 - Soc Nuclear Med
The present translational study aimed to verify whether serial 18 F-FDG PET/CT predicts
doxorubicin cardiotoxicity. Methods: Fifteen athymic mice were treated intravenously with saline …
doxorubicin cardiotoxicity. Methods: Fifteen athymic mice were treated intravenously with saline …
[HTML][HTML] An increase in myocardial 18-fluorodeoxyglucose uptake is associated with left ventricular ejection fraction decline in Hodgkin lymphoma patients treated with …
M Sarocchi, M Bauckneht, E Arboscello… - Journal of Translational …, 2018 - Springer
Background Doxorubicin (DOX)-based chemotherapy for Hodgkin lymphoma (HL) yields
excellent disease-free survival, but poses a substantial risk of subsequent left ventricular (LV) …
excellent disease-free survival, but poses a substantial risk of subsequent left ventricular (LV) …
Potential of creatine or phosphocreatine supplementation in cerebrovascular disease and in ischemic heart disease
M Balestrino, M Sarocchi, E Adriano, P Spallarossa - Amino acids, 2016 - Springer
Creatine is of paramount importance for maintaining and managing cellular ATP stores in both
physiological and pathological states. Besides these “ergogenic” actions, it has a number …
physiological and pathological states. Besides these “ergogenic” actions, it has a number …
Arterial hypertension in cancer: The elephant in the room
G Tini, M Sarocchi, G Tocci, E Arboscello… - International journal of …, 2019 - Elsevier
The great therapeutical success achieved by oncology is counterbalanced by growing evidences
of cardiovascular (CV) toxicity due to many antineoplastic treatments. Cardiac adverse …
of cardiovascular (CV) toxicity due to many antineoplastic treatments. Cardiac adverse …
[HTML][HTML] How to monitor cardiac complications of immune checkpoint inhibitor therapy
P Spallarossa, M Sarocchi, G Tini… - Frontiers in …, 2020 - frontiersin.org
Immune-checkpoint inhibitors (ICIs) represent a successful paradigm in the treatment of
cancer. ICIs elicit an immune response directed against cancer cells, by targeting the so-called …
cancer. ICIs elicit an immune response directed against cancer cells, by targeting the so-called …
[PDF][PDF] Identification and management of immune checkpoint inhibitor–related myocarditis: use troponin wisely
P Spallarossa, G Tini, M Sarocchi… - Journal of Clinical …, 2019 - clf1.medpagetoday.com
Background Myocarditis is an uncommon, but fearsome complication of immune checkpoint
inhibitors (ICPis) because it may result in life-threatening heart failure, cardiogenic shock, …
inhibitors (ICPis) because it may result in life-threatening heart failure, cardiogenic shock, …
Potential cardiac risk of immune‐checkpoint blockade as anticancer treatment: what we know, what we do not know, and what we can do to prevent adverse effects
…, M Deidda, D Mele, M Sarocchi… - Medicinal Research …, 2018 - Wiley Online Library
Cancer immunotherapy has become a well‐established treatment option for some cancers
after the development of a family of drugs targeting the so‐called immune checkpoints, such …
after the development of a family of drugs targeting the so‐called immune checkpoints, such …
Baseline cardio-oncologic risk assessment in breast cancer women and occurrence of cardiovascular events: the HFA/ICOS risk tool in real-world practice
G Tini, A Cuomo, A Battistoni, M Sarocchi… - International Journal of …, 2022 - Elsevier
Background the European Society of Cardiology Heart Failure Association (HFA) together
with the International Cardio-Oncology Society (ICOS) proposed charts for baseline CV risk …
with the International Cardio-Oncology Society (ICOS) proposed charts for baseline CV risk …
BMI and acute kidney injury post transcatheter aortic valve replacement: unveiling the obesity paradox
…, M Vercellino, R Della Bona, M Sarocchi… - Journal of …, 2021 - journals.lww.com
Aims Acute kidney injury (AKI) may complicate transcatheter aortic valve replacement (TAVR)
leading to higher mortality. The relationship between AKI, obesity, and mortality, however, …
leading to higher mortality. The relationship between AKI, obesity, and mortality, however, …