User profiles for Mathieu L. Lepage
Mathieu L. LepageCNRS | Univ. Toulouse III - Paul Sabatier Verified email at cnrs.fr Cited by 779 |
A broadly applicable cross-linker for aliphatic polymers containing C–H bonds
Addition of molecular cross-links to polymers increases mechanical strength and improves
corrosion resistance. However, it remains challenging to install cross-links in low-functionality …
corrosion resistance. However, it remains challenging to install cross-links in low-functionality …
Recent advances in 18F radiochemistry: a focus on B-18F, Si-18F, Al-18F, and C-18F radiofluorination via spirocyclic iodonium ylides
V Bernard-Gauthier, ML Lepage… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Straightforward radiosynthesis protocols for 18 F-labeled radiopharmaceuticals are an
indispensable but often overlooked prerequisite to successfully perform molecular imaging …
indispensable but often overlooked prerequisite to successfully perform molecular imaging …
Direct access to MIDA acylboronates through mild oxidation of MIDA vinylboronates
ML Lepage, S Lai, N Peressin… - Angewandte Chemie …, 2017 - Wiley Online Library
Acylboronate esters/trifluoroborates represent an elusive class of boronates that are of
increasing interest for both fundamental study as well as applications at the interface of chemistry …
increasing interest for both fundamental study as well as applications at the interface of chemistry …
Iminosugar‐Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels
ML Lepage, JP Schneider, A Bodlenner… - … A European Journal, 2016 - Wiley Online Library
A series of cyclopeptoid‐based iminosugar clusters has been evaluated to finely probe the
ligand content‐dependent increase in α‐mannosidase inhibition. This study led to the largest …
ligand content‐dependent increase in α‐mannosidase inhibition. This study led to the largest …
Structural Basis of Outstanding Multivalent Effects in Jack Bean α‐Mannosidase Inhibition
Multivalent design of glycosidase inhibitors is a promising strategy for the treatment of
diseases involving enzymatic hydrolysis of glycosidic bonds in carbohydrates. An essential …
diseases involving enzymatic hydrolysis of glycosidic bonds in carbohydrates. An essential …
[HTML][HTML] Flexible polyfluorinated bis-diazirines as molecular adhesives
Motivated by a desire to develop flexible covalent adhesives that afford some of the same
malleability in the adhesive layer as traditional polymer-based adhesives, we designed and …
malleability in the adhesive layer as traditional polymer-based adhesives, we designed and …
[HTML][HTML] A sustainable polymer and coating system based on renewable raw materials
Paints and coatings are widely used in modern society and their current production is
mainly dependent on the petrochemical industry. The establishment of processes using …
mainly dependent on the petrochemical industry. The establishment of processes using …
Giant Glycosidase Inhibitors: First‐and Second‐Generation Fullerodendrimers with a Dense Iminosugar Shell
…, A Joosten, M Holler, ML Lepage… - … A European Journal, 2018 - Wiley Online Library
The multivalent effect in glycosidase inhibition is a new topic in glycoscience that has
emerged a few years ago, with the discovery of neoglycoclusters displaying strong binding …
emerged a few years ago, with the discovery of neoglycoclusters displaying strong binding …
[HTML][HTML] Synthesis of the first examples of iminosugar clusters based on cyclopeptoid cores
ML Lepage, A Meli, A Bodlenner… - Beilstein journal of …, 2014 - beilstein-journals.org
Cyclic N-propargyl α-peptoids of various sizes were prepared by way of macrocyclizations of
linear N-substituted oligoglycines. These compounds were used as molecular platforms to …
linear N-substituted oligoglycines. These compounds were used as molecular platforms to …
Toward 18F‐Labeled Theranostics: A Single Agent that Can Be Labeled with 18F, 64Cu, or 177Lu
We report a single‐molecule radiotracer that can be labeled independently with 18 F‐fluoride
or radiometals ( 64 Cu, 177 Lu) in a single step. A prostate‐specific membrane antigen (…
or radiometals ( 64 Cu, 177 Lu) in a single step. A prostate‐specific membrane antigen (…