Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis

…, H Okada, W Carlson, P Bey, M Rusckowski… - Nature medicine, 2012 - nature.com
Molecules associated with the transforming growth factor β (TGF-β) superfamily, such as
bone morphogenic proteins (BMPs) and TGF-β, are key regulators of inflammation, apoptosis …

Tumor pretargeting in mice using 99mTc-labeled morpholino, a DNA analog

…, N Liu, S Gupta, M Rusckowski… - Journal of Nuclear …, 2002 - Soc Nuclear Med
Over the past several years, investigators in this laboratory and elsewhere have been studying
tumor localization by pretargeting with streptavidin and biotin or with avidin and biotin. …

In vitro and in vivo assessment of 99mTc-UBI specificity for bacteria

…, L Meléndez-Alafort, YM Zhang, M Rusckowski… - Nuclear medicine and …, 2003 - Elsevier
Technetium-99m labeled ubiquicidin peptide 29-41 ( 99m Tc-UBI) is a cationic human
antimicrobial peptide fragment that has been shown to bind bacteria in vitro and accumulates at …

In Vitro and in Vivo Evaluation of a Technetium-99m-Labeled Cyclic RGD Peptide as a Specific Marker of αVβ3 Integrin for Tumor Imaging

ZF Su, G Liu, S Gupta, Z Zhu, M Rusckowski… - Bioconjugate …, 2002 - ACS Publications
Three amino acids residues, Arg-Gly-Asp (RGD), in vitronectin and fibronectin show affinity
for α V β 3 integrins expressed in vascular endothelial cells. That tumor growth can …

Investigations of a 99mTc-labeled bacteriophage as a potential infection-specific imaging agent

M Rusckowski, S Gupta, G Liu, S Dou… - Journal of Nuclear …, 2004 - Soc Nuclear Med
Because bacteriophages (phages) have a natural specificity for bacteria, it may be possible
to develop radiolabeled phages as infection-specific agents. Methods: The M13 phage was …

[PDF][PDF] Technetium-99m labeling of DNA oligonucleotides

…, CL Smith, CR Cantor, M Rusckowski - Journal of Nuclear …, 1995 - Soc Nuclear Med
After labeling, the ability of the DNAs to bind to streptavidin through the biotinmoieties and
to hybridIzewiththeir compie mentary DNAin saline was retained for both radiolabels as …

Influence of different chelators (HYNIC, MAG3 and DTPA) on tumor cell accumulation and mouse biodistribution of technetium-99m labeled to antisense DNA

YM Zhang, N Liu, ZH Zhu, M Rusckowski… - European journal of …, 2000 - Springer
We have shown recently that cell accumulation in culture of antisense DNA is strongly
influenced by the presence of a 99m Tc-MAG 3 group for radiolabeling. We have now compared …

Detection of Aspergillus fumigatus pulmonary fungal infections in mice with 99mTc-labeled MORF oligomers targeting ribosomal RNA

…, Y Liu, S Dou, DJ Hnatowich, M Rusckowski - Nuclear medicine and …, 2013 - Elsevier
PURPOSE: Invasive aspergillosis is a major cause of infectious morbidity and mortality in
immunocompromised patients. The fungus Aspergillus fumigatus (A. fumigatus) is the primary …

Investigation of four 99mTc-labeled bacteriophages for infection-specific imaging

M Rusckowski, S Gupta, G Liu, S Dou… - Nuclear medicine and …, 2008 - Elsevier
INTRODUCTION: This study investigates radiolabeled bacteriophages for specific detection
of infection through gamma imaging. Previously, a 99m Tc-labeled M13 phage …

[PDF][PDF] Directly and Indirectly Technetium-99m-Labeled Antibodies A—Comparison of In Vitro and Animal In Vivo Properties

…, G Mardirossian, M Rusckowski… - Journal of Nuclear …, 1993 - Soc Nuclear Med
MATERIALSAND METHODS This investigation was performed with B72. 3 and Cl 10in their
intact IgG form. The B72. 3 antibody, an IgGl, is directed against the antigen tag-72 which is …