Objective Angiotensin II induces myocardial hypertrophy. We hypothesized that blockade of
angiotensin II subtype 1 (AT 1) receptors by the AT 1-receptor antagonist irbesartan would …

Objectives: Mitochondrial abnormalities have been described in cardiac tissue of patients
with heart failure. These changes may result from chronic hypoxia. Our goal was to determine …

One hundred five patients underwent mitral valve replacement for relief of isolated mitral
regurgitation between 1974 and 1979. There were 4 in-hospital deaths (4 percent) and 12 late …

The ability to predict early postoperative left ventricular size and function in patients with
isolated aortic or mitral regurgitation was determined utilizing multigated blood pool imaging …

QT interval (QTI) is the surrogate electrocardiographic index ofventricular repolarization and
its duration under normal conditions is mainly determined by expression, properties, and …

Ischemic preconditioning (IPC) protects myocardium from ischemia reperfusion injury by
activating mitochondrial K ATP channels. However, the mechanism underlying the protective …

Background. Coenzyme Q 10 (CoQ 10 ) protects myocardium from ischemia-reperfusion (IR)
injury as evidenced by improved recovery of mechanical function, ATP, and …

A new NMR technique for nondestructive, noninvasive, nonradioactive concurrent measurements
of blood flow and several energy‐dependent metabolites were applied to in situ cat …

Angiotensin type 1 receptor antagonists have direct effects on the autonomic nervous
system and myocardium. Because of this, we hypothesized that irbesartan would reduce QT …

The mechanism by which the fructose analogue 2,5-anhydro-D-mannitol (2,5-AM) elicits
feeding behavior was investigated by studying its metabolism and biochemical effects in liver. …