Aims Conventional late gadolinium enhancement (LGE) cardiac magnetic resonance can
detect myocardial infarction and some forms of non-ischaemic myocardial fibrosis. However, …

Rapid innovations in cardiovascular magnetic resonance (CMR) now permit the routine
acquisition of quantitative measures of myocardial and blood T1 which are key tissue …

Background Disturbances in the myocardial extracellular volume fraction (ECV), such as
diffuse or focal myocardial fibrosis or edema, are hallmarks of heart disease. Diffuse ECV …

Parametric mapping techniques provide a non-invasive tool for quantifying tissue
alterations in myocardial disease in those eligible for cardiovascular magnetic resonance (CMR). …

Background Commercially available software for cardiovascular image analysis often has
limited functionality and frequently lacks the careful validation that is required for clinical …

Objectives : The aim of this study was to determine whether cardiac magnetic resonance (CMR)
in vivo T1 mapping can measure myocardial area at risk (AAR) compared with …

Background Diffuse myocardial fibrosis, and to a lesser extent global myocardial edema,
are important processes in heart disease which are difficult to assess or quantify with …

Previous studies using echocardiography in healthy subjects have reported conflicting data
regarding the percentage of the stroke volume (SV) of the left ventricle (LV) resulting from …

Background Quantification of myocardial blood flow requires knowledge of the amount of
contrast agent in the myocardial tissue and the arterial input function (AIF) driving the delivery …

Background— Experimental studies have shown that induction of hypothermia before
reperfusion of acute coronary occlusion reduces infarct size. Previous clinical studies, however, …