The human E48 antigen, highly homologous to the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion.

RH Brakenhoff, M Gerretsen, EM Knippels… - The Journal of cell …, 1995 - rupress.org
The E48 antigen, a putative human homologue of the 20-kD protein present in desmosomal
preparations of bovine muzzle, and formerly called desmoglein III (dg4), is a promising …

[PDF][PDF] Labeling of monoclonal antibodies with rhenium-186 using the MAG3 chelate for radioimmunotherapy of cancer: a technical protocol

GWM Visser, M Gerretsen, JDM Herscheid… - Journal of Nuclear …, 1993 - Soc Nuclear Med
Radio-Nuclide-Center(RNC), Free University; and Depamnent of Otolwyngolo@ j/Head and
Neck Surgery, Free University Hospita!@ Ainsterdam@ The Netherlands further …

Lansoprazole 30mg versus omeprazole 40mg in the treatment of reflux oesophagitis grade II, III and IVa (a Dutch multicentre trial)

CJ Mulder, W Dekker, M Gerretsen… - European journal of …, 1996 - journals.lww.com
Objectives: To compare the efficacy and safety of lansoprazole 30 mg daily (LAN30) and
omeprazole 40mg daily (OME40) in the treatment of moderate (Savary–Miller grade II) as well …

Evidence for a role of the monoclonal antibody E48 defined antigen in cell-cell adhesion in squamous epithelia and head and neck squamous cell carcinoma

AHGJ Schrijvers, M Gerretsen, JM Fritz… - Experimental cell …, 1991 - Elsevier
Monoclonal antibody (MAb) E48 recognizes a 20- to 22-kDa antigen expressed by human
squamous and transitional epithelia and their neoplastic counterparts. Histochemical …

Two target sites for protein binding in the promoter region of a cell cycle regulated human H1 histone gene

…, KL Wright, RF Massung, M Gerretsen… - Nucleic acids …, 1988 - academic.oup.com
The 5' region of a cell cycle regulated human H1 histone gene appears to contain at least six
promoter DNA elements that are shared with some, but not all human core (H2A, H2B, H3 …

186Re-labeled Monoclonal Antibody E48 Immunoglobulin G-mediated Therapy of Human Head and Neck Squamous Cell Carcinoma Xenografts

M Gerretsen, GWM Visser, M van Walsum… - Cancer research, 1993 - AACR
In our laboratory, a solid-phase synthesis of 186 Re-mercaptoacetyltriglycine for reproducible
and aseptic production of stable 186 Re-monoclonal antibody conjugates was recently …

The feasibility of radioimmunotherapy of head and neck cancer

M Gerretsen, JJ Quak, RH Brakenhoff, GB Snow… - European Journal of …, 1994 - Elsevier
Since the introduction of the hybridoma technology by Kohler and Milstein (Nature 1975,
256, 495–497), tremendous effort has been put in the realisation of Ehrlich's concept of the …

Progress in radioimmunotherapy of head and neck-cancer

…, R DEBREE, M GERRETSEN… - Oncology …, 1994 - spandidos-publications.com
There is an urgent need for an effective adjuvant systemic therapy for the treatment of patients
with advanced head and neck cancer. This study shows that therapy based on the use of …

Detection of squamous cell carcinoma xenografts in nude mice by radiolabeled monoclonal antibody E48

JJ Quak, M Gerretsen, AHGJ Schrijvers… - … –Head & Neck …, 1991 - jamanetwork.com
• We recently produced the monoclonal antibody E48 as a specific reagent for squamous
cell carcinomas. In our ongoing investigations to use E48 for clinical tumor detection and …

[HTML][HTML] Monoclonal antibodies for diagnosis and therapy of squamous cell carcimona of the head and neck

…, H Leverstein, A Schrijvers, M Gerretsen… - Sao Paulo Medical …, 1994 - SciELO Brasil
O grupo de carcinomas espinocelulares da cabeça e pescoço em pacientes com alto risco
de desenvolver metástases à distância, tem sido bem definidos do ponto de vista …