Translating TRAIL-receptor targeting agents to the clinic

MW den Hollander, JA Gietema, S de Jong… - Cancer letters, 2013 - Elsevier
The extrinsic apoptotic pathway can be activated by the endogenous ligand TRAIL (Tumor
Necrosis Factor (TNF)-Related Apoptosis-Inducing Ligand) by binding to the death receptors …

TGF-β antibody uptake in recurrent high-grade glioma imaged with 89Zr-fresolimumab PET

MW den Hollander, F Bensch… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Transforming growth factor–β (TGF-β) signaling is involved in glioma development. The
monoclonal antibody fresolimumab (GC1008) can neutralize all mammalian isoforms of TGF-β, …

53BP1 as a potential predictor of response in PARP inhibitor-treated homologous recombination-deficient ovarian cancer

…, RHT Koornstra, A Jager, MW den Hollander… - Gynecologic …, 2019 - Elsevier
Objective Poly(ADP-ribose) polymerase (PARP) inhibitors have shown substantial activity in
homologous recombination- (HR-) deficient ovarian cancer and are undergoing testing in …

[HTML][HTML] Serial FLT PET imaging to discriminate between true progression and pseudoprogression in patients with newly diagnosed glioblastoma: a long-term follow …

CG Brahm, MW den Hollander, RH Enting… - European journal of …, 2018 - Springer
Purpose Response evaluation in patients with glioblastoma after chemoradiotherapy is
challenging due to progressive, contrast-enhancing lesions on MRI that do not reflect true tumour …

Bleomycin-induced pulmonary changes on restaging computed tomography scans in two thirds of testicular cancer patients show no correlation with fibrosis markers

MW den Hollander, NDL Westerink, S Lubberts… - The …, 2016 - academic.oup.com
Background. In metastatic testicular cancer patients treated with bleomycin, etoposide, and
cisplatin (BEP) chemotherapy, bleomycin-induced pneumonitis is a well-known and …

[HTML][HTML] A phase 1 study of PARP-inhibitor ABT-767 in advanced solid tumors with BRCA1/2 mutations and high-grade serous ovarian, fallopian tube, or primary …

…, MJA de Jonge, IME Desar, MW Den Hollander… - Investigational new …, 2018 - Springer
Purpose This phase 1 study examined safety, pharmacokinetics (PK), and efficacy of the
poly(ADP-ribose) polymerase (PARP) inhibitor ABT-767 in patients with advanced solid tumors …

89zr-GC1008 PET imaging and GC1008 treatment of recurrent glioma patients.

MW den Hollander, F Bensch, AWJM Glaudemans… - 2013 - ascopubs.org
2050 Background: Transforming growth factor-β (TGF-β) signaling is involved in glioma
development. GC1008 is a monoclonal antibody that has demonstrated significant neutralization …

[BOOK][B] An Entrance for the Eyes: Space and Meaning in Seventeenth-Century Dutch Art

M Hollander - 2002 - books.google.com
… of professional di‹culties: John Hollander and Anne Hollander (who first let me loose in
museums at the appropriate age of three), Elizabeth Hollander, Natalie Charkow, and Thomas …

A phase Ib study of the VEGF receptor tyrosine kinase inhibitor tivozanib and modified FOLFOX-6 in patients with advanced gastrointestinal malignancies

…, MM Cotreau, AL Strahs, MW Den Hollander… - Clinical colorectal …, 2015 - Elsevier
Background Tivozanib hydrochloride (tivozanib) is a potent and selective tyrosine kinase
inhibitor of all 3 vascular endothelial growth factor receptors with antitumor activity additive to 5-…

Public and private life in the art of Pieter de Hooch

M Hollander - Netherlands Yearbook for History of Art/Nederlands …, 2000 - brill.com
In the quiet corner of a city, two women are working in the courtyard of a house (fig. I). A
servant carries a pitcher and bucket, squinting in the sun's glare and walking toward the low …