Nurr1 is a member of the nuclear receptor superfamily of transcription factors that is
expressed predominantly in the central nervous system, including developing and mature …

FoxO (forkhead box O; forkhead members of the O class) are transcription factors that function
under the control of insulin/insulin-like signalling. FoxO factors have been associated with …

Insulin is best known for its role in peripheral glucose homeostasis. Less studied, but not less
important, is its role in the central nervous system. Insulin and its receptor are located in the …

Forkhead transcription factors of the FoxO-group are associated with cellular processes like
cell cycle progression and DNA-repair. FoxO function is regulated by protein kinase B (PKB) …

We identified the LIM homeodomain transcription factor Lmx1b in the mesencephalic
dopamine (mesDA) systems of embryos and adults. Analysis of spatiotemporal expression in …

The mesencephalic dopaminergic (mesDA) system regulates behavior and movement control
and has been implicated in psychiatric and affective disorders. We have identified a bicoid-…

Dopaminergic neurons located in the ventral mesodiencephalon are essential for the
control of voluntary movement and the regulation of emotion, and are severely affected in …

A major advance in biomedical science and diagnosis was accomplished with the development
of in vivo techniques to image radiolabeled molecules, but limited spatial resolution has …

The mesencephalic dopamine (mesDA) system is involved in the control of movement and
behavior. The expression of Pitx3 in the brain is restricted to the mesDA system and the gene …

Support of ageing neurons by endogenous neurotrophic factors such as glial cell line–derived
neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF) may determine …