German multicenter study investigating 177Lu-PSMA-617 radioligand therapy in advanced prostate cancer patients

…, A Pfestroff, M Luster, U Lützen, M Marx… - Journal of Nuclear …, 2017 - Soc Nuclear Med
177 Lu-labeled PSMA-617 is a promising new therapeutic agent for radioligand therapy (RLT)
of patients with metastatic castration-resistant prostate cancer (mCRPC). Initiated by the …

Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease

…, B Schulte, WH Pan, N Mishra, M Zuhayra, M Marx… - Gut, 2019 - gut.bmj.com
Objective Vedolizumab, a monoclonal antibody directed against the integrin heterodimer
α4β7, is approved for the treatment of Crohn’s disease and ulcerative colitis. The efficacy of …

[HTML][HTML] Analysis and classification of B-cell infiltrates in lupus and ANCA-associated nephritis

OM Steinmetz, J Velden, U Kneissler, M Marx, A Klein… - Kidney international, 2008 - Elsevier
Intrarenal B cell infiltrates resembling secondary lymphoid tissue have been found in several
forms of inflammatory kidney disease. Their role in renal inflammation is not well defined, …

[HTML][HTML] Automated synthesis of [68Ga]Ga-FAPI-46 without pre-purification of the generator eluate on three common synthesis modules and two generator types

A Alfteimi, U Lützen, A Helm, M Jüptner, M Marx… - EJNMMI radiopharmacy …, 2022 - Springer
Background The recent development of quinoline-based radiotracers, which act as
fibroblast activation protein inhibitors (FAPIs), has shown promising preclinical and clinical …

[HTML][HTML] Case report: arterial wall inflammation in atherosclerotic cardiovascular disease is reduced by olamkicept (sgp130Fc)

DM Schulte, GH Waetzig, H Schuett, M Marx… - Frontiers in …, 2022 - frontiersin.org
Inflammation is a strong driver of atherosclerotic cardiovascular disease (ASCVD). There is
a large unmet need for therapies that prevent or reduce excessive inflammation while …

[HTML][HTML] Pre-and intratherapeutic predictors of overall survival in patients with advanced metastasized castration-resistant prostate cancer receiving Lu-177-PSMA-617 …

R Wrenger, M Jüptner, M Marx, Y Zhao, M Zuhayra… - BMC urology, 2022 - Springer
Background Systemic Lutetium-177 prostate-specific membrane antigen-617 radioligand
therapy (Lu-177-PSMA-617-RLT) is a novel treatment approach in patients suffering from …

Evaluation of the diagnostic value of preoperative sentinel lymph node (SLN) imaging in penile carcinoma patients without palpable inguinal lymph nodes via single …

CM Naumann, C Colberg, M Jüptner, M Marx… - … Oncology: Seminars and …, 2018 - Elsevier
Background Sentinel lymph node (SLN) biopsy represents a well-established diagnostic tool
for the assessment of lymphatic metastasis. Correct pre- and intraoperative visualization of …

Pioglitazone induces cell growth arrest and activates mitochondrial apoptosis in human uterine leiomyosarcoma cells by a peroxisome proliferator-activated receptor γ …

U Lützen, Y Zhao, K Lucht, M Zuhayra, M Marx… - Naunyn-Schmiedeberg's …, 2017 - Springer
The peroxisome proliferator-activated receptor γ (PPARγ) agonists, thiazolidinediones,
including pioglitazone (PIO) exhibit anti-tumour activities in cancer cells. The present study …

Value and efficiency of sentinel lymph node diagnostics in patients with penile carcinoma with palpable inguinal lymph nodes as a new multimodal, minimally invasive …

U Lützen, M Zuhayra, M Marx, Y Zhao… - European journal of …, 2016 - Springer
Purpose The international guidelines recommend sentinel lymph node biopsy (SLNB) for
lymph node staging in penile cancer with non-palpable inguinal lymph nodes (LN) but it is not …

[HTML][HTML] PSMA-617 inhibits proliferation and potentiates the 177Lu-PSMA-617-induced death of human prostate cancer cells

…, J Culman, I Cascorbi, N Nithack, M Marx… - Naunyn-schmiedeberg's …, 2023 - Springer
The human prostate–specific membrane antigen (PSMA) is substantially up-regulated in
metastatic prostate cancer (PCa) cells. PSMA can be targeted by 177 Lu conjugated to PSMA-…