[HTML][HTML] Real-time in vivo imaging of invasive- and biomaterial-associated bacterial infections using fluorescently labelled vancomycin

M Van Oosten, T Schäfer, JAC Gazendam… - Nature …, 2013 - nature.com
Invasive and biomaterial-associated infections in humans are often difficult to diagnose and
treat. Here, guided by recent advances in clinically relevant optical imaging technologies, …

Molecular fluorescence-guided surgery of peritoneal carcinomatosis of colorectal origin: a single-centre feasibility study

…, A Jorritsma-Smit, M van Oosten… - The Lancet …, 2016 - thelancet.com
Background Optimum cytoreductive surgery combined with hyperthermic intraperitoneal
chemotherapy (HIPEC) is essential for the curative treatment of peritoneal carcinomatosis of …

Targeted imaging of bacterial infections: advances, hurdles and hopes

M van Oosten, M Hahn, LMA Crane… - FEMS microbiology …, 2015 - academic.oup.com
Bacterial infections represent an increasing problem in modern health care, in particular
due to ageing populations and accumulating bacterial resistance to antibiotics. Diagnosis is …

[HTML][HTML] Selecting potential targetable biomarkers for imaging purposes in colorectal cancer using TArget Selection Criteria (TASC): a novel target identification tool

M van Oosten, LMA Crane, J Bart… - Translational …, 2011 - Elsevier
Peritoneal carcinomatosis (PC) of colorectal origin is associated with a poor prognosis.
However, cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy is …

Distinct roles of phenol-soluble modulins in spreading of Staphylococcus aureus on wet surfaces

…, A de Jong, G Buist, M van Oosten… - Applied and …, 2013 - Am Soc Microbiol
The human pathogen Staphylococcus aureus is renowned for the rapid colonization of
contaminated wounds, medical implants, and food products. Nevertheless, little is known about …

[HTML][HTML] The effect of chemotherapy on expression of folate receptor-alpha in ovarian cancer

LMA Crane, HJG Arts, M Van Oosten, PS Low… - Cellular oncology, 2012 - Springer
Background Folate receptor alpha (FR-α) has been identified as a potential target in ovarian
cancer for diagnostic and therapeutic purposes, based on its overexpression in serous …

Ultrafast Photoclick Reaction for Selective 18F-Positron Emission Tomography Tracer Synthesis in Flow

…, GB Spoelstra, JM van Dijl, M van Oosten… - Journal of the …, 2021 - ACS Publications
The development of very fast, clean, and selective methods for indirect labeling in PET
tracer synthesis is an ongoing challenge. Here we present the development of an ultrafast …

[HTML][HTML] Preclinical studies and prospective clinical applications for bacteria-targeted imaging: the future is bright

…, AW Friedrich, B Sinha, M van Oosten - Clinical and translational …, 2016 - Springer
Bacterial infections are a frequently occurring and major complication in human healthcare,
in particular due to the rapid increase of antimicrobial resistance and the emergence of pan-…

[HTML][HTML] Fighting Staphylococcus aureus infections with light and photoimmunoconjugates

…, AR Horswill, KP Francis, GM van Dam, M van Oosten… - JCI insight, 2020 - ncbi.nlm.nih.gov
Infections caused by multidrug-resistant Staphylococcus aureus, especially methicillin-resistant
S. aureus (MRSA), are responsible for high mortality and morbidity worldwide. Resistant …

[HTML][HTML] First evaluation of a commercial multiplex PCR panel for rapid detection of pathogens associated with acute joint infections

…, L Gard, GA Kampinga, M van Oosten… - Journal of Bone and …, 2023 - jbji.copernicus.org
Background: prompt recognition and identification of the causative microorganism in acute
septic arthritis of native and prosthetic joints is vital to increase the chances of successful …