BACKGROUND Contractile function of the ex vivo, isolated left atrium (LA) has been described
by a time-varying elastance, but this atrial chamber property has not been shown in vivo. …

Background Many of the cardiovascular manifestations of thyroid hormone excess resemble
those produced by sympathoadrenal stimulation. The objective of this study was to …

Objectives. The purpose of this study was to identify the effects of altered loading conditions
on left atrial appendage flow velocities. Background. Although studies have suggested that …

OBJECTIVES The purpose of this study was to understand the significance of an effective
atrial systole and the interactions between atrial and ventricular function. BACKGROUND The …

Rapid atrial pacing produces atrial systolic and diastolic failure characterized by absent atrial
booster pump function, increased atrial chamber stiffness, enhanced atrial conduit function, …

Objective: To determine the left atrial mechanical and biochemical adaptations to congestive
heart failure, 10 dogs with rapid atrial and ventricular pacing and seven control dogs were …

The objective of this study was to examine the hypothesis that long-term, rapid atrial pacing
produces a model of atrial systolic and diastolic dysfunction but does not alter ventricular …

Human chymase is a serine proteinase that converts angiotensin (Ang) I to Ang II independent
of angiotensin converting enzyme (ACE) in vitro. The effects of chymase on systemic …

The transcriptional, posttranscriptional, and related functional effects of thyroid hormone on
primate myocardium are poorly understood. Therefore, we studied the effects of thyroid …

It has been postulated that in cardiac tamponade, the hemodynamic effects of compression
of the right heart chambers and great veins are more important than are the effects of left …