Learning Objectives After completing this course, the reader will be able to: Discuss the
technical advances that have led to recent rapid developments in monoclonal antibody imaging …

Human epidermal growth factor receptor (HER)2 imaging with radiolabeled trastuzumab
might support HER2-targeted therapy. It is, however, frequently questioned whether HER2 …

Bispecific antibodies (bsAbs) are antibodies that bind two distinct epitopes to cancer.. For
use in oncology, one bsAb has been approved and 57 bsAbs are in clinical trials, none of …

More than 50 monoclonal antibodies (mAbs), including several antibody–drug conjugates,
are in advanced clinical development, forming an important part of the many molecularly …

Intraplaque angiogenesis is associated with the occurrence of atherosclerotic plaque rupture.
Cardiovascular molecular imaging can be used for the detection of rupture-prone plaques. …

A carcinoid crisis is a severe complication of the carcinoid syndrome that can arise in
patients with advanced metastatic neuroendocrine tumors. It can be initiated by stress, …

[ 177 Lu]Lu-DOTA-NNV003, a radioimmunoconjugate targeting CD37, is developed as novel
radioimmunotherapy (RIT) treatment for patients with B cell non-Hodgkin’s lymphoma (NHL…

Programmed cell death protein-1/ligand-1 (PD-1/PD-L1) blockade is effective in a subset of
patients with several tumor types, but predicting patient benefit using approved diagnostics is …

Vascular endothelial growth factor (VEGF), released by tumor cells, is an important growth
factor in tumor angiogenesis. The humanized monoclonal antibody bevacizumab blocks VEGF…

Purpose The cardiac and antineoplastic effects of trastuzumab may be related to specific
uptake of trastuzumab in myocardium and tumor tissue, respectively. We evaluated whether …