Introduction. Converging evidence suggests that PDE-4 (phosphodiesterase subtype 4)
plays a crucial role in regulating cognition via the PDE-4-cAMP cascade signaling involving …

BACKGROUND: When treatment-refractory schizophrenia shows an insufficient response to
a trial of clozapine, clinicians commonly add a second antipsychotic, despite the lack of …

Cytokine storm can result from cancer immunotherapy or certain infections, including COVID-19.
Though short-term immune-related adverse events are routinely described, longer-term …

Background: Medical students are at a significant risk of experiencing psychological issues,
such as burnout. Over the past few years, more studies have been conducted on this topic, …

Background: No systematic review or meta-analysis has yet been performed to examine the
global prevalence of nomophobia by population, by instrument. Thus, this review was …

Background There is evidence that culture deeply affects beliefs about mental illnesses'
causes, treatment, and help-seeking. We aimed to explore and compare knowledge, attitudes …

Purpose of Review Several studies have found that medical students have a significant
prevalence of sleep issues, such as poor sleep quality, excessive daytime sleepiness, and …

Background: Converging evidence suggests dysregulation of epigenetics in terms of histone-mediated
acetylation/deacetylation imbalance in Parkinson’s disease (PD). Targeting …

Background Several reports suggest that altered mitochondrial DNA copy number (mtDNA-cn),
a common biomarker for aberrant mitochondrial function, is implicated in autism …

Recently, social media has heightened interest toward the public health issue of cognition
changes in aging. The estimated global prevalence of Alzheimer disease or Alzheimer …