Objective Macrophages show extreme heterogeneity and different subsets have been
characterized by their activation route and their function. For instance, macrophage subsets are …

OBJECTIVE: Macrophages are decisive in the chronic inflammatory processes that drive
atherogenesis. The purpose of this study was to explore the presence and spatial distribution of …

Nonalcoholic steatohepatitis (NASH) involves liver lipid accumulation (steatosis) combined
with hepatic inflammation. The transition towards hepatic inflammation represents a key step …

Atherosclerosis is a progressive disorder of the arterial wall and the underlying cause of
cardiovascular diseases such as heart attack and stroke. Today, atherosclerosis is recognized …

Atherosclerosis is now generally accepted as a chronic inflammatory condition. The transcription
factor NF-κB is a key regulator of inflammation, immune responses, cell survival, and …

The transition from stable to rupture-prone and ruptured atherosclerotic plaques involves many
processes, including an altered balance between inflammation and fibrosis. An important …

After radiotherapy treatment, there is an increased incidence of localized atherosclerosis in
patients with Hodgkin's disease, breast cancer, and head and neck cancer. Here, we …

Rationale: Several studies have suggested a role for the gut microbiota in inflammation and
atherogenesis. A causal relation relationship between gut microbiota, inflammation, and …

Inflammatory cytokines are well-recognized mediators of atherosclerosis. Depending on the
pathological context, type I interferons (IFNs; IFNα and IFNβ) exert either pro- or anti-…

Rationale: Viral myocarditis results from an adverse immune response to cardiotropic
viruses, which causes irreversible myocyte destruction and heart failure in previously healthy …