Background Patients with neutropenia resulting from chemotherapy for acute myelogenous
leukemia or the myelodysplastic syndrome are at high risk for difficult-to-treat and often fatal …

Background Isatuximab is an anti-CD38 monoclonal antibody approved in combination with
pomalidomide–dexamethasone and carfilzomib–dexamethasone for relapsed or refractory …

Progressive multifocal leucoencephalopathy (PML) is a serious and usually fatal CNS
infection caused by JC polyoma virus. CD4+ and CD8+ T lymphopenia, resulting from HIV …

Background Chronic graft-versus-host disease (GVHD) is the leading cause of later illness
and death after allogeneic hematopoietic stem-cell transplantation. We hypothesized that the …

Purpose We conducted an international, randomized, phase III trial to evaluate the efficacy
and safety of consolidation with yttrium-90 ( 90 Y)–ibritumomab tiuxetan in patients with …

The potential therapeutic value of cell-based therapy with mesenchymal stem cells (MSC)
has been reported in mouse models of polymicrobial peritoneal sepsis. However, the …

CD57 + expression in T lymphocytes has been recognized for decades as a marker of in vitro
replicative senescence. In recent years, accumulating evidences have pointed on the utility …

It has been proven that mesenchymal stromal cells (MSCs) can differentiate into tenocytes.
Attempts to repair tendon lesions have been performed, mainly using scaffold carriers in …

In this paper, we propose an absolutely innovative technique for the electrical stimulation of
cells, based on piezoelectric nanoparticles. Ultrasounds are used to impart mechanical …

Current treatment of hematologic malignancies involves rather unspecific chemotherapy,
frequently resulting in severe adverse events. Thus, modern clinical research focuses on …