In vitro and in vivo evaluation of an alumina–zirconia composite for arthroplasty applications

O Roualdes, ME Duclos, D Gutknecht, L Frappart… - Biomaterials, 2010 - Elsevier
In order to improve the reliability and the mechanical properties of orthopaedic hip prosthesis,
new ceramic composites starting with nanosized powders of alumina and zirconia have …

[HTML][HTML] The Ratio 1660/1690 cm−1 Measured by Infrared Microspectroscopy Is Not Specific of Enzymatic Collagen Cross-Links in Bone Tissue

D Farlay, ME Duclos, E Gineyts, C Bertholon… - PloS one, 2011 - journals.plos.org
In postmenopausal osteoporosis, an impairment in enzymatic cross-links (ECL) occurs,
leading in part to a decline in bone biomechanical properties. Biochemical methods by high …

[HTML][HTML] Synovial extracellular vesicles: Structure and role in synovial fluid tribological performances

…, CI Matei, MM Sava, S Filali, ME Duclos… - International Journal of …, 2022 - mdpi.com
The quality of the lubricant between cartilaginous joint surfaces impacts the joint’s mechanistic
properties. In this study, we define the biochemical, ultrastructural, and tribological …

[HTML][HTML] Radiographic assessment of the femorotibial joint of the CCLT rabbit experimental model of osteoarthritis

…, F Collard, PA Maitre, O Roualdes, ME Duclos… - BMC medical …, 2010 - Springer
Background The purposes of the study were to determine the relevance and validity of in
vivo non-invasive radiographic assessment of the CCLT (Cranial Cruciate Ligament …

18F-FDG PET SUVmax correlates with osteosarcoma histologic response to neoadjuvant chemotherapy: preclinical evaluation in an orthotopic rat model

…, AV Decouvelaere, J Monteil, ME Duclos… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Assessment of osteosarcoma response to neoadjuvant chemotherapy is performed by
histopathologic analysis after surgical resection of the primary tumor. The purpose of this study …

Nonclinical safety assessment of repeated administration and biodistribution of ChAd3‐EBO‐Z Ebola candidate vaccine

C Planty, G Chevalier, MÈ Duclos… - Journal of Applied …, 2020 - Wiley Online Library
ChAd3‐EBO‐Z is an investigational adenovirus‐based vaccine for the prevention of Ebola
virus disease. Two nonclinical studies were performed to evaluate the biodistribution, local …

Preclinical profile of GM102, a first-in-class antibody targeting AMHRII in ovarian cancers.

…, A Pelegrin, D Decaudin, C de Romeuf, ME Duclos… - 2016 - ascopubs.org
e23196 Background: Expression of anti-Müllerian hormone receptor (AMHRII) is described
in gynecologic cancers, tumors which are largely infiltrated by immune myeloid cells. Based …

Safety Assessment of an Anti-Müllerian Hormone Receptor II Therapeutic Antibody

R FORSTER, ME DUCLOS, JF PROST - 日本毒性学会学術年会 第 45 …, 2018 - jstage.jst.go.jp
GM102 is a first-in-class glyco-engineered monoclonal antibody (mAb) targeting Anti-Müllerian
Hormone Receptor II (AMHRII) and is in development for the treatment of gynecological …

[CITATION][C] Retrospective analysis of guinea pig systemic anaphylaxis results

J Descotes, ME Duclos, V Haag, R Forster - Toxicology Letters, 2014 - infona.pl
… Jacques Descotes, Marie-Eve Duclos, Valérie Haag, Roy Forster …

The Staphylococcus aureus Autoinducer-2 Synthase LuxS Is Regulated by Ser/Thr Phosphorylation

…, AJ Cozzone, K Fütterer, B Duclos… - Journal of …, 2010 - Am Soc Microbiol
The Staphylococcus aureus autoinducer-2 (AI-2) producer protein LuxS is phosphorylated
by the Ser/Thr kinase Stk1 at a unique position, Thr14. The enzymatic activity of the …