Accurate delineation of the intraprostatic gross tumor volume (GTV) is a prerequisite for
treatment approaches in patients with primary prostate cancer (PCa). Prostate-specific …

Accurate delineation of the intraprostatic gross tumour volume (GTV) is a prerequisite for
treatment approaches in patients with primary prostate cancer (PCa). Prostate-specific …

Nucleosomes compact and regulate access to DNA in the nucleus, and are composed of
approximately 147 bases of DNA wrapped around a histone octamer 1 , 2 . Here we report a …

The transition metal copper (Cu) is essential for all living organisms but is toxic when present
in excess. To identify Cu deficiency responses comprehensively, we conducted genome-…

… Department of Otorhinolaryngology and Finnish Institute of Occupational Health, Helsinki
University Hospital, Helsinki, Finland, now working at Center for Applied Genomics, The …

Zinc ions are required to maintain the biological activity of numerous proteins. However,
when mislocalized or accumulated in excess, Zn 2+ ions are toxic because of adventitious …

Estimating within-city variability in air pollution concentrations is important. Land use regression
(LUR) models are able to explain such small-scale within-city variations. Transparency …

10.7554/eLife.06100.001 The vascular plant Arabidopsis thaliana is a central genetic model
and universal reference organism in plant and crop science. The successful integration of …

DESY Hamburg operates a test beam facility with three independent beam lines at the DESY
II synchrotron. It is world-wide one of very few facilities providing test beams in the GeV …

Objectives: Exposure to high concentrations of persistent organochlorines may cause fetal
toxicity, but the evidence at low exposure levels is limited. Large studies with substantial …